Molecular Organic Synthesis
Available in 2013
|Callaghan Campus||Semester 1|
Previously offered in 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004
The development of modern synthetic materials, whether they be new drugs for the treatment of cancer or for the latest synthetic fabric, requires a knowledge of molecular organic synthesis. Students will develop pre-existing skills (from CHEM2310) to a higher level examining a range of synthetic transformations for functional group transformations, carbon-carbon bond formation and skeletal rearrangements, emphasising the chemo- and stereo-selectivity and mechanism of these reactions. A logical, applied approach backed up by laboratory work will be utilised to emphasise key concepts. Students will also be introduced to the application of molecular organic synthesis to biological systems. Selected literature classics of chemical synthesis will also be included.
The course forms part of the accredited degree program required for Membership of Royal Australian Chemical Institute Inc. and Chartered Chemist qualifications.
This course has compulsory course components and students must:
1. must participate in and submit laboratory reports for the established minimum requirements and obtain a minimum passing grade of 50%; and
2. obtain a minimum passing grade of 40% in the final, end-of-semester examination for the course.
In order to participate in this course, students must complete a compulsory Health and Safety requirement. Students will receive full information on this compulsory component in the course outline provided by the school.
|Objectives||On successful completion of this course, students will be able:
1. to develop expertise relevant to the professional practice of chemistry
2. to provide a greater understanding of the range and reactions of organic compounds
3. to develop an understanding of the processes of synthesis and mechanisms of reactions in organic chemistry
4. to develop an understanding of the role of the chemist in the synthesis of new compounds and study of their reactions
5. to provide an understanding of the concepts of chemoselectivity and stereoselectivity of organic reactions
6. to provide laboratory experience with some methods employed in organic synthesis
7. to extend skills in procedures applied in synthetic tasks and identification of organic compounds
8. to expand skills in the scientific method of planning, developing, conducting, reviewing and reporting experiments
9. to extend understanding of the professional and safety responsibilities residing in working with organic compounds.
|Content||The course involves study of:
1) Functional Group Chemistry:
a) reactions for functional group transformation
b) nucleophilic addition and substitution at carbonyl groups
c) oxidation-reduction reactions
2) Organic Reaction Mechanisms:
a) mechanisms for organic reactions
b) bond-forming and skeletal rearrangement reactions
c) chemoselectivity and stereoselectivity
a) systematic approaches to synthesis
b) protecting groups
c) multistep synthesis and illustrative examples
|Modes of Delivery||Internal Mode|
|Teaching Methods||Problem Based Learning
|Contact Hours||Lecture: for 2 hour(s) per Week for Full Term
Laboratory: for 3 hour(s) per Week for Full Term
Tutorial: for 1 hour(s) per Week for Full Term
|Timetables||2013 Course Timetables for CHEM3310|