The University of Newcastle, Researcher report.

Researcher: Professor Adam McCluskey
School: School of Environmental and Life Sciences
Personal URL: http://www.newcastle.edu.au/staff/profile/adam.mccluskey.html

Funded Projects

Please note, only grants administered through the University of Newcastle Research Office are recorded here. For a more complete picture of the researcher's grant history a Personal URL may be supplied, above.

Research Team Initial Year Duration (Years) Funding Body/Client Award Type Title of Project Collaborating Partners Total Cash $ Total Inkind $
Professor Adam McCluskey;Professor Phillip Robinson 3 National Health & Medical Research Council Project Grant Mechanism Of Action Of Dynamin Ring Stabilizer Compounds Controlling The Actin Cytoskeleton   318510  
Conjoint Professor Alison Jones;Professor Adam McCluskey;Professor Paul Dastoor 3 Defence Science and Technology Organisation Centres of Excellence Centre of excellence in biological and chemical threat mitigation   150000  
Professor Adam McCluskey;Ms Megan Chircop;Professor Phillip Robinson;Doctor Jennette Sakoff 3 National Health & Medical Research Council Project Grant The role of clathrin in the spindle assembly checkpoint and as an anticancer target   245100  
Professor Adam McCluskey 3 National Health & Medical Research Council Project Grant Sulfonadyn-based dynamin I-specific inhibitors and epilepsy   403931  
Professor Adam McCluskey;Professor Ronald Quinn;Professor Eileen McLaughlin;Associate Professor Brett Nixon 1 University of Newcastle Equipment Grant Bioaffinity mass spectrometry infrastructure to identify small molecules binding to therapeutic targets   125000  
Professor Adam McCluskey;Professor Eileen McLaughlin;Associate Professor Peter Lewis;Ms Belinda Nixon;Doctor Shaun Roman;Doctor Jennette Sakoff;Doctor Ian Grainge 2012 1 National Health & Medical Research Council Equipment Grant Ultrasonic Homogenizer System and -80 ºC Freezers for chemical and biological sample storage   10000  
Professor Adam McCluskey;Professor Phillip Robinson;Professor Terence O'Brien;Ms Megan Chircop;Doctor Jennette Sakoff 2011 3 National Health & Medical Research Council Development Grants Development of pthaladyn-based dynamin I-selective inhibitors for treatment of epilepsy   544831  
Professor Eileen McLaughlin;Associate Professor Peter Lewis;Professor Adam McCluskey;Professor Keith Jones;Associate Professor Brett Nixon;Doctor Shaun Roman;Doctor Jennette Sakoff;Doctor Ian Grainge;Doctor Janet Holt;Ms Xiao Yang 2011 1 National Health & Medical Research Council Equipment Grant Eppendorf mastercycler pro with thermomixer comfort and 5430R centrifuge   15000  
Professor Adam McCluskey 2011 1 University of Newcastle Linkage Pilot Research Grant Restocking the Cupboard - Next generation Antibiotics   9758  
Associate Professor Peter Lewis;Professor Nicholas Dixon;Professor Eileen McLaughlin;Professor Adam McCluskey;Associate Professor Aaron Oakley;Professor Paul Foster;Laureate Professor Robert Aitken;Associate Professor Jennifer Beck;Dr Michael Kelso;Professor Graham Nicholson;Associate Professor Elizabeth Harry;Professor Ian Charles;Associate Professor Steven Djordjevic 2011 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) Establishment of a comprehensive regional biophysical analysis facility   500000  
Professor Adam McCluskey 2011 1 University of Newcastle Near Miss Grant Development of clathrin inhibitors as novel endocytosis inhibitors   25000  
Laureate Professor Robert Aitken;Doctor Mark Baker;Professor Kenneth Beagley;Professor Adam McCluskey 2011 3 Australian Research Council Discovery Projects Chemical principles underpinning a spermostatic-microbiostatic agent capable of preventing pregnancy and the spread of sexually transmitted disease   735000  
Professor Adam McCluskey 2011 3 Cancer Council NSW Research Program Dynamin as a new drug target for the treatment of glioblastoma   96000  
Professor Adam McCluskey 2011 4 Australian Research Council Linkage Projects Characterisation of a new class of antimicrobial agent for multidrug-resistant infections   147500  
Associate Professor Peter Lewis;Professor Nicholas Dixon;Professor Eileen McLaughlin;Professor Adam McCluskey;Associate Professor Aaron Oakley;Professor Paul Foster;Laureate Professor Robert Aitken;Associate Professor Jennifer Beck;Dr Michael Kelso;Professor Graham Nicholson;Associate Professor Elizabeth Harry;Professor Ian Charles;Associate Professor Steven Djordjevic 2011 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding Establishment of a comprehensive regional biophysical analysis facility   230000  
Professor Adam McCluskey 2011 4 Australian Research Council Linkage Projects Characterisation of a new class of antimicrobial agent for multidrug-resistant infections   214000  
Professor Adam McCluskey;Professor Raymond Rose;Doctor Nicole Verrills;Associate Professor Peter Lewis;Doctor Shaun Roman;Doctor Warwick Belcher;Doctor Jennette Sakoff;Professor Eileen McLaughlin;Professor Christopher Grof;Doctor Ian Grainge 2011 5 University of Newcastle Priority Research Centre Chemical Biology   443100  
Laureate Professor Robert Aitken;Professor Eileen McLaughlin;Professor Adam McCluskey 2010 3 Found Animals Foundation Inc Michelson Grants in Reproductive Biology Development of a humane non-surgical sterilization method for domestic animals   1006825  
Professor Adam McCluskey;Professor Phillip Robinson;Assoc. Prof Martin Larsen 2010 3 Australian Research Council Discovery Projects Streamlining the dynamin epilepsy drug pipeline   438000  
Professor Adam McCluskey;Laureate Professor Robert Aitken;Professor Paul Dastoor;Professor Phillip Robinson;Professor Eileen McLaughlin;Emeritus Professor Geoffrey Lawrance;Associate Professor Marcel Maeder;Associate Professor Richard Dunstan;Doctor Shaun Roman;Doctor Rob Atkin;Doctor Clovia Holdsworth;Doctor Mark Baker;Doctor Nicole Verrills;Professor Gottfried Otting;Associate Professor Brett Nixon;Doctor Xiaojing Zhou;Ms Megan Chircop;Doctor Warwick Belcher 2010 1 University of Newcastle Equipment Grant An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry   280000  
Professor Adam McCluskey;Laureate Professor Robert Aitken;Professor Paul Dastoor;Professor Phillip Robinson;Professor Eileen McLaughlin;Emeritus Professor Geoffrey Lawrance;Associate Professor Marcel Maeder;Associate Professor Richard Dunstan;Doctor Shaun Roman;Doctor Rob Atkin;Doctor Clovia Holdsworth;Doctor Mark Baker;Doctor Nicole Verrills;Professor Gottfried Otting;Associate Professor Brett Nixon;Doctor Xiaojing Zhou;Ms Megan Chircop;Doctor Warwick Belcher 2010 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry   500000  
Doctor Mark Baker;Professor Adam McCluskey 2010 1 Hunter Children`s Research Foundation Research Grant The design of novel, affinity-based technology to specifically isolate phosphotyrosine-containing pedtides   25000  
Doctor Mark Baker;Laureate Professor Robert Aitken;Professor Adam McCluskey;Associate Professor Brett Nixon;Professor John Rostas;Professor Eileen McLaughlin 2010 1 National Health & Medical Research Council Equipment Grant Waters, Ultra high performance liquid chromatography system (nano-Aquity)   30000  
Professor Adam McCluskey 2010 1 Australian Cancer Research Foundation Cancer Research Grant Australian Cancer Research Foundation Cancer Research Grant   1012636  
Professor Adam McCluskey 2010 1 Ramaciotti Foundations Major Initiative for Biomedical Research The 2009 Ramaciotti Major Initiative Biomedical Research Award   300000  
Professor Adam McCluskey;Miss Lacey Hizartzidis;Miss Kelly Young 2010 1 John Morris Scientific Pty Ltd Research Grant Centre for Kinomics   25000  
Professor Adam McCluskey;Ms Megan Chircop 2009 1 James S. McDonnell Foundation Research Award Dynamin as a new drug target for he treatment of glioblastoma   74457  
Laureate Professor Robert Aitken;Professor Adam McCluskey;Doctor Mark Baker;Doctor Nicole Verrills;Associate Professor Marcel Maeder;Doctor Xiaojing Zhou;Professor Eileen McLaughlin;Associate Professor Brett Nixon;Doctor Shaun Roman;Professor Raymond Rose;Associate Professor Richard Dunstan;Professor Christopher Grof;Professor Roger Smith;Conjoint Professor Peter Gibson;Conjoint Professor Alison Jones;Professor Michael Calford;Professor Keith Jones;Doctor Rick Thorne;Emeritus Professor Peter Dunkley;Professor Paul Foster;Conjoint Professor Leonie Ashman;Professor Gordon Burns;Associate Professor Phillip Dickson;Professor John Rostas;Professor Rodney Scott;Doctor Paul Tooney;Professor Philip Hansbro;Professor Pablo Moscato;Professor Paul Dastoor;Associate Professor Peter Lewis 2009 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry   50000  
Laureate Professor Robert Aitken;Professor Adam McCluskey;Doctor Mark Baker;Doctor Nicole Verrills;Associate Professor Marcel Maeder;Doctor Xiaojing Zhou;Professor Eileen McLaughlin;Associate Professor Brett Nixon;Doctor Shaun Roman;Professor Raymond Rose;Associate Professor Richard Dunstan;Professor Christopher Grof;Professor Roger Smith;Conjoint Professor Peter Gibson;Conjoint Professor Alison Jones;Professor Michael Calford;Professor Keith Jones;Doctor Rick Thorne;Emeritus Professor Peter Dunkley;Professor Paul Foster;Conjoint Professor Leonie Ashman;Professor Gordon Burns;Associate Professor Phillip Dickson;Professor John Rostas;Professor Rodney Scott;Doctor Paul Tooney;Professor Philip Hansbro;Professor Pablo Moscato;Professor Paul Dastoor;Associate Professor Peter Lewis 2009 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry   495000  
Professor Adam McCluskey 2009 1 National Health & Medical Research Council Development Grants Development of novel anti-epileptic drugs targeting vesicular endocytosis   66200  
Professor Adam McCluskey 2009 3 National Health & Medical Research Council Project Grant Development of dynamin inhibitors as novel therapies for epilepsy   306001  
Professor Adam McCluskey 2009 2 Epilepsy Foundation of America New Therapy Grants Program Preclinical new chemical entities as novel anti-epileptic drugs targeting dynamin   132924  
Professor Adam McCluskey;Doctor Michael Bowyer;Doctor Clovia Holdsworth;Dr Christopher Lennard 2008 3 Australian Federal Police Linkage Projects Partner funding Chemical listening devices: Novel sensors targeting the clandestine manufacture and transport of illicit drugs and explosives   105000  
Professor Adam McCluskey;Doctor Michael Bowyer;Doctor Clovia Holdsworth;Dr Christopher Lennard;Ms Katherine Booker 2008 3 Australian Research Council Linkage Projects Chemical listening devices: Novel sensors targeting the clandestine manufacture and transport of illicit drugs and explosives   378942  
Professor Adam McCluskey;Professor Robin Gasser;Dr Jennette Sakoff 2008 3 Genetic Technologies Limited Linkage Projects Partner funding The discovery and validation of novel drug classes against parasites of major economic importance   270000  
Professor Adam McCluskey;Professor Robin Gasser;Dr Jennette Sakoff;Mr Ian Holland;Mr Mark Tarleton 2008 3 Australian Research Council Linkage Projects The discovery and validation of novel drug classes against parasites of major economic importance   670000  
Conjoint Professor Stephen Ackland;Conjoint Professor Leonie Ashman;Professor John Forbes;Conjoint Professor James Denham;Conjoint Professor Peter Hersey;Professor Gordon Burns;Professor Adam McCluskey;Doctor Nicole Verrills 2008 2 Hunter Medical Research Institute MRSP Infrastructure Grant HMRI Cancer Research Program - MRSP Infrastructure   1031290  
Professor Paul Dastoor;Professor John O'Connor;Professor Bruce King;Professor Adam McCluskey;Doctor Warwick Belcher;Professor Catherine Stampfl;Dr Jeffrey Reimers;Assoc. Prof Alexander Hamilton;Dr Adam Micolich;Doctor Christopher Fell;Dr Scott Watkins;Dr Mark Bown;Dr Anton Stampfl;Dr Peter Evans 2008 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) Integrated surface fabrication and characterisation laboratory   750000  
Professor Paul Dastoor;Professor John O'Connor;Professor Bruce King;Professor Adam McCluskey;Doctor Warwick Belcher;Professor Catherine Stampfl;Dr Jeffrey Reimers;Assoc. Prof Alexander Hamilton;Dr Adam Micolich;Doctor Christopher Fell;Dr Scott Watkins;Dr Mark Bown;Dr Anton Stampfl;Dr Peter Evans 2008 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding Partner contributions for Integrated surface fabrication and characterisation laboratory   320000  
Professor Adam McCluskey;Doctor Clovia Holdsworth;Doctor Michael Bowyer;Mr Dougal Cleland 2007 4 Entech Industries Pty Ltd Postgraduate Research Scholarship Selective Detection and Removal of Organochlorine Residues via MIPs   105000  
Professor Paul Dastoor;Professor Adam McCluskey;Associate Professor Erica Wanless;Associate Professor Scott Donne;Doctor John Holdsworth 2006 5 University of Newcastle Priority Research Centre PRC - Priority Research Centre for Organic Electronics & OrganoBiosensors   403990  
Professor Adam McCluskey 2006 1 University of Newcastle Travel Grant BIT's 4th Annual Congress of International Drug Discovery Science & Technology 25 May - 2 June 2006   2400  
Professor Adam McCluskey 2006 1 University of Newcastle Near Miss Grant Chemical Interventions in Neurological Diseases?   20000  
Professor Adam McCluskey 2006 3 National Health & Medical Research Council Project Grant Consequences of Dynamin 2 PH Domain Dysfunction in Charcot-Marie-Tooth Neuropathy   217500  
Laureate Professor Robert Aitken;Professor Eileen McLaughlin;Associate Professor Peter Lewis;Conjoint Associate Professor Renate Griffith;Professor Raymond Rose;Emeritus Professor John Patrick;Associate Professor David McCurdy;Professor Adam McCluskey;Emeritus Professor Ellak Von Nagy-Felsobuki;Emeritus Professor Peter Dunkley;Associate Professor Phillip Dickson;Professor John Rostas;Conjoint Professor Leonie Ashman;Professor Gordon Burns;Professor Paul Foster;Conjoint Professor Peter Gibson;Professor Roger Smith;Professor Alistair Sim;Doctor Paul Tooney;Dr Fraser Ross 2005 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation   207189  
Professor Adam McCluskey;Doctor Michael Bowyer;Mr Ryan Shaw;Ms Kathleen Wright 2004 3 Australian Research Council Linkage Projects In-field sensors for the detection of illicit drugs   171336  
Professor Adam McCluskey;Doctor Michael Bowyer 2004 3 Australian Federal Police Linkage Projects Partner funding In-field sensors for the detection of illicit drugs   45000  
Professor Adam McCluskey;Doctor Michael Bowyer;Dr M O'Shea 2004 3 Australian Research Council Linkage Projects Selective detection and removal of contaminants that have an adverse impact on Australian raw sugar quality   190000  
Professor Adam McCluskey 2004 1 Ramaciotti Foundations Major Equipment Award Improving Drug Development: New Approaches to Rapid Development of Novel Lead Compounds   27542  
Conjoint Professor Leonie Ashman;Professor Adam McCluskey 2004 1 Hunter Medical Research Institute Research Grant New drugs targeting protein kinases   17000  
Professor Adam McCluskey 2004 1 AINSE (Australian Institute of Nuclear Science & Engineering) Use of Facilities Only Radiocarbon dating of heroin samples as a tool to verify the conversion to alternative crops.   5820  
Professor Adam McCluskey;Doctor Michael Bowyer 2004 3 Bureau of Sugar Experiment Stations Linkage Projects Partner funding Selective detection and removal of contaminants that have adverse impact on Australian raw sugar quality   51000  
Professor Alistair Sim;Laureate Professor Robert Aitken;Emeritus Professor Peter Dunkley;Professor John Rostas;Associate Professor Phillip Dickson;Conjoint Professor Leonie Ashman;Professor Roger Smith;Professor Gordon Burns;Professor Adam McCluskey;Doctor Paul Tooney;Dr Fraser Ross;Professor Raymond Rose 2004 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) Biacore3000-Expansion of Proteomics Facility   187341  
Professor Adam McCluskey;Assoc. Prof David Young;Doctor Jennette Sakoff 2003 1 Australian Research Council Discovery Projects High Pressure and Fluorous Approaches to fostriecin libraries: New Therapeutic Opportunities.   50000  
Professor Adam McCluskey 2003 3 National Health & Medical Research Council Project Grant Dynamin inhibitors as tools for dissecting the endocytic pathways neurons   165000  
Professor Adam McCluskey 2003 2 Australian Federal Police Research Grant Implementation of a Methamphetamine Method for the Australian Federal Police   230309  
Professor Adam McCluskey 2003 1 Australian Federal Police Equipment Grant Implementation of a Methamphetamine Method for the Australian Federal Police   30000  
Professor Adam McCluskey 2002 1 University of Newcastle Project Grant Development of new therapeutic agents for the treatment of epilepsy   8000  
Professor Adam McCluskey;Dr P Keller;Professor Roger Smith;Dr A Ruhmann 2002 3 National Health & Medical Research Council Project Grant Antagonist of Corticotrophin Releasing Hormone as Therapeutic Agents for the Prevention of Premature Birth in Humans   375000  
Professor Adam McCluskey;Conjoint Professor Stephen Ackland;Doctor Jennette Sakoff 2002 1 University of Newcastle Project Grant New targets for chemotherapy: anti-cancer drugs that target protein phosphatases   10000  
Emeritus Professor Geoffrey Lawrance;Dr I Hamilton;Professor Adam McCluskey 2002 3 Australian Research Council Discovery Projects Devevelopement and Use of Ionic Liquids in Metal Recovery from Ores, Concentrates and Mattes.   205000  
Professor Adam McCluskey 2001 1 University of Newcastle Project Grant Development of new drugs for the prevention of premature birth   10000  
Professor Adam McCluskey 2001 1 University of Newcastle Project Grant Environmentally friendly ('Green') organic chemistry: Development of novel methodologies and reagents.   5000  
Professor Adam McCluskey 2001 1 University of Newcastle Travel Grant 92nd American Association for Cancer Research Annual Meeting, USA 24-28 March 2001   2400  
Professor Adam McCluskey 2001 2 Grape & Wine Research and Development Corporation Project Grant Selective detection of Trichloroanisole and other flavour contaminants in wines using molecularly imprinted polymer technology.   30268  
Professor Adam McCluskey;Professor Roger Smith 2000 1 University of Newcastle Project Grant Synthesis of Drugs for Prevention of Pre-Term Delivery.   10000  
Professor Adam McCluskey 2000 1 University of Newcastle Project Grant Towards Green Chemistry: The Development of Environmentally Organic Synthesis.   7000  
Professor Adam McCluskey;Doctor Michael Bowyer 2000 1 Grape & Wine Research and Development Corporation Project Grant Selective detection of Trichloroanisole and other flavour contaminants in wines using molecularly imprinted polymer technology.   26950  
Professor John Rostas;Professor Adam McCluskey 1999 1 Bio-Rad Laboratories Pty Ltd (Australia) Research Grant RMC Collab Partner.Development of a Versatile, Sensitive, Non-Isotopic Method for Detecting Phosphorylated and Glucosylated Serines in Proteins & Peptides.   10000  
Professor Adam McCluskey;Doctor Michael Bowyer 1999 1 Grape & Wine Research and Development Corporation Project Grant Selective detection of Trichloroanisole and other flavour contaminants in wines using molecularly imprinted polymer technology   20000  
Doctor Jennette Sakoff;Professor Adam McCluskey;Conjoint Professor Stephen Ackland 1999 1 Hunter Medical Research Institute Research Grant Selective Inhibitors of Protein Phosphatases as Anti-cancer agents   25000  
Professor Adam McCluskey;Professor Roger Smith 1999 1 University of Newcastle Project Grant Rapid Microscale Synthesis of Drugs for the Prevention of Pre-Term Delivery   13500  
Professor John Rostas;Professor Adam McCluskey 1999 1 University of Newcastle Collaborative Research Grant Development of a Versatile, Sensitive, Non-Isotopoic Method for Detecting Phosphorylated and Glycosylated Serines in Proteins and Peptides   10000  
Professor Adam McCluskey 1998 1 University of Newcastle Project Grant Computer Modelling and Graphical Representation of the Three Dimensional Structure of Protein Phosphatases   9000  
Professor Adam McCluskey 1998 1 University of Newcastle Travel Grant XVth EFMC International Symposium on Medicinal Chemistry, Scotland 6-10 September 1998   2500  
Professor Adam McCluskey;Dr P Keller;Professor Roger Smith 1998 3 University of Newcastle Special Scholarship Initiative Grants Low molecular weight ligands for corticotrophin releasing hormone receptors: Drugs for intervention during human pregnancy   47664  
Professor Adam McCluskey 1997 1 University of Newcastle Project Grant Development Of A Novel, Photolytic Oxidising Agent For Use In Synthetic Chemistry.   7000  
Professor Roger Smith;Professor Adam McCluskey;Professor Alan Boura 1997 1 Australian Research Council Small Grant Computer Asisted Design and Chemical Synthesis of Novel Therapeutic Agents Affecting Pregnancy the Duration of Human Pregnancy   16000  
Professor Adam McCluskey; Ian Leitch 1997 1 Ramaciotti Foundations Research Grant Design and Synthesis of Novel Corticotropin-Releasing Hormone Receptors Agaonists/Antagonists: Development of New Therapeutic Agents   15000  
Professor Adam McCluskey 1996 1 University of Newcastle New Staff Grant Design & Synthesis ofNovel Protein Phosphatase 1 & Protein Phosphatase 2A Inhibitors   12500  

Research Higher Degree Supervision

For a more complete picture of the researcher's supervision history a Personal URL may be supplied at the top of this page.

Current Student Supervision

Program Supervision Level Research Topic
PhD (Chemistry) Principal Supervisor 1. Dynamin-l Inhibitors from Sessile Marine Invertebrates; 2. Chemotaxonomy of Cystophora spp.
PhD (Chemistry) Principal Supervisor A Chemical Biology Approach to Novel Inhibitors of Clathrin
PhD (Chemistry) Principal Supervisor A mechanistic insight into the reaction between CO2 and amines
PhD (Chemistry) Co-Supervisor Bioassay Guided Purification and Identification of Lead Compounds from Marine Organisms
PhD (Chemistry) Principal Supervisor Development of Novel Anti-Epileptic Drugs Targeting Dynamic GTPase
PhD (Chemistry) Principal Supervisor Disrupting Endocytosis: Towards Novel Inhibitors of the Endocytic Proteins Dynamin and Clathrin
PhD (Chemistry) Principal Supervisor Molecularly Imprinted Polymers for Polychlorinated Biphenyls
PhD (Chemistry) Sole Supervisor Novel Inhibitors of Dynamin GTPase
PhD (Chemistry) Co-Supervisor Signal Transduction in Molecularly Imprinted Polymers
PhD (Chemistry) Principal Supervisor Synthesis and Evaluation of Norcantharidin and Acrylonitrile Derivatives as Potential Anti-cancer Agents
PhD (Chemistry) Co-Supervisor Synthesis of Regioregular Poly-3-Hexylthiophene Using Flow Chemistry for Incorporation into Organic Photo Voltaic Cells
PhD (Chemistry) Principal Supervisor Synthesis, Characterisation and Evaluation of Biphenyl Monomers for Molecular Imprinting Applications
PhD (Chemistry) Principal Supervisor The Medicinal Chemistry of Clathrin Inhibitors
PhD (Medicine) Co-Supervisor The Characterisation and Classification of Residual Marks on Bone Inflicted by New, Worn and Re-Sharpened Bladed Weapons

Total Equivalent Full-time Student Units (EFTSU):

Supervision Level EFTSU
PhD 6.800

Student Completions

NB - the completions shown here are only those for the University of Newcastle obtained since 2001.

Program Year Research Topic
PhD (Chemistry) 2004 Design and Synthesis of Potential CRHR1 Antagonists
PhD (Chemistry) 2004 Development Towards Structurally Unprecedented Corticotropin Releasing Hormone Type-1 Receptor Antagonists
PhD (Chemistry) 2005 Chemotaxonomy of the brown algal genus Cyclophoria
PhD (Chemistry) 2006 Cantharidin Analogues: Potential Therapeutic Agents
PhD (Chemistry) 2006 Ionic Liquids for Explosive Technologies
PhD (Chemistry) 2006 New Routes To Precious Metal Recovery Using Ionic Liquids
PhD (Chemistry) 2006 Novel Inhibitors of Dynamin GTPase
PhD (Chemistry) 2007 Design and Synthesis of Novel Dynamin GTPase Inhibitors
PhD (Chemistry) 2008 Design and Synthesis of Molecularly Imprinted Polymers for the Selective Recognition of Small Chloro-Arene Contaminants
PhD (Chemistry) 2008 Ionic Liquids for Synthesis and Metal Recovery
PhD (Chemistry) 2009 Norcantharidin Analogues: PP1 and PP2A Inhibition and Potential Therapeutic Development
PhD (Chemistry) 2010 Characterisation and Improved Performance of Molecularly Imprinted Polymers Prepared Using Room Temperature Ionic Liquids
PhD (Chemistry) 2010 Optimisation of Molecularly Imprinted Polymeric Films for the Detection of L-Ephedrine
PhD (Chemistry) 2010 Towards the Development of a Benzylpiperazine Specific Molecular Imprinted Polymer
M Philosophy (Chemistry) 2011 Novel Inhibitors of Clathrin Mediated Endocytosis

Research Publications

Please note, the publications listed here:
(1) relate to the researcher's position at the University of Newcastle only
(2) are for selected categories of publications, and
(3) relate to publication year 1998, onwards.
For a more complete picture of the researcher's publication history a Personal URL may be supplied at the top of this page.

Journal Article

Tarleton Mark, McCluskey Adam, ’A flow chemistry route to 2-phenyl-3-(1H-pyrrol-2-yl)propan-1-amines’, Tetrahedron Letters, 52 1583-1586 (2011) [C1]

Gordon Christopher Peter, Young Kelly A, Robertson Mark James, Hill Timothy Adrian, McCluskey Adam, ’An Ugi-intramolecular Diels-Alder route to highly substituted tetrahydroepoxyisoindole carboxamides’, Tetrahedron, 67 554-561 (2011) [C1]

Wright Anthony D, McCluskey Adam, Robertson Mark James, Macgregor Kylie A, Gordon Christopher Peter, Guenther Jana, ’Anti-malarial, anti-algal, anti-tubercular, anti-bacterial, anti-photosynthetic, and anti-fouling activity of diterpene and diterpene isonitriles from the tropical marine sponge Cymbastela hooperi’, Organic and Biomolecular Chemistry, 9 400-407 (2011) [C1]

Gordon Christopher Peter, Young Kelly A, Hizartzidis Lacey, Deane Fiona M, McCluskey Adam, ’Investigation of the one-pot synthesis of quinolin-2-(1H)-ones and the discovery of a variation of the three-component Ugi reaction’, Organic and Biomolecular Chemistry, 9 1419-1428 (2011) [C1]

Macgregor Kylie A, McCluskey Adam, ’Ionic liquids accelerate access to N-substituted-1,8-naphthalimides’, Tetrahedron Letters, 52 767-769 (2011) [C1]

Tarleton Mark, Gilbert Jayne, Robertson Mark James, McCluskey Adam, Sakoff Jennette A, ’Library synthesis and cytotoxicity of a family of 2-phenylacrylonitriles and discovery of an estrogen dependent breast cancer lead compound’, MedChemComm, 2 31-37 (2011) [C1]

Campbell Bronwyn E, Tarleton Mark John, Gordon Christopher Peter, Sakoff Jennette A, Gilbert Jayne, McCluskey Adam, Gasser Robin B, ’Norcantharidin analogues with nematocidal activity in Haemonchus contortus’, Bioorganic and Medicinal Chemistry Letters, 21 3277-3281 (2011) [C1]

Von Kleist Lisa, Stahlschmidt Wiebke, Bulut Haydar, Gromova Kira, Puchkov Dmytro, Robertson Mark James, Macgregor Kylie Anne, Tomlin Nikolay, Pechstein Arndt, Chau Ngoc, Chircop Megan, Sakoff Jennette Anne, Von Kries Jens Peter, Saenger Wolfram, Krausslich Hans-Georg, Shupliakov Oleg, Robinson Phillip J, McCluskey Adam, Haucke Volker, ’Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition’, Cell, 146 471-484 (2011) [C1]

Campbell Bronwyn E, Hofmann Andreas, McCluskey Adam, Gasser Robin B, ’Serine/threonine phosphatases in socioeconomically important parasitic nematodes - Prospects as novel drug targets?’, Biotechnology Advances, 29 28-39 (2011) [C1]

Gordon Christopher Peter, Byrne Nolene, McCluskey Adam, ’A facile, protic ionic liquid route to N-substituted 5-hydroxy-4-methyl-3-oxoisoindoline-1-carboxamides and N-substituted 3-oxoisoindoline-4-carboxylic acids’, Green Chemistry, 12 1000-1006 (2010) [C1]

Chircop Megan, Malladi Chandra S, Lian Audrey T, Page Scott L, Zavortink Michael, Gordon Christopher Peter, McCluskey Adam, Robinson Phillip J, ’Calcineurin activity is required for the completion of cytokinesis’, Cellular and Molecular Life Sciences, 67 3725-3737 (2010) [C1]

Howes Mark T, Kirkham Matther, Riches James, Cortese Katia, Walser Piers J, Simpson Fiona, Hill Michelle M, Jones Alun, Lundmark Richard, Lindsay Margaret R, Hernandez-Deviez Delia J, Hadzic Gordana, McCluskey Adam, Bashir Rumasia, Liu Libin B, Pilch Paul, McMahon Harvey, Robinson Phillip J, Hancock John F, Mayor Satyajit, Parton Robert G, ’Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells’, Journal of Cell Biology, 190 675-691 (2010) [C1]

Hill Timothy Adrian, Mariana Anna, Gordon Christopher Peter, Odell Luke, Robertson Mark James, McGeachie Andrew B, Chau Ngoc, Daniel James A, Gorgani Nick N, Robinson Phillip J, McCluskey Adam, ’Iminochromene inhibitors of Dynamins I and II GTPase activity and Endocytosis’, Journal of Medicinal Chemistry, 53 4094-4102 (2010) [C1]

Turner Nicholas William, Holdsworth Clovia Isabel, Donne Scott Wilfred, McCluskey Adam, Bowyer Michael Christian, ’Microwave induced MIP synthesis: comparative analysis of thermal and microwave induced polymerisation of caffeine imprinted polymers’, New Journal of Chemistry, 34 686-692 (2010) [C1]

Thaqi Ali, Scott Janet L, Gilbert Jayne, Sakoff Jennette Anne, McCluskey Adam, ’Synthesis and biological activity of Delta-5,6-norcantharimides: Importance of the 5,6-bridge’, European Journal of Medicinal Chemistry, 45 1717-1723 (2010) [C1]

Joshi Sanket, Perera Swetha, Gilbert Jayne, Smith Charlotte M, Mariana Anna, Gordon Christopher Peter, Sakoff Jennette A, McCluskey Adam, Robinson Phillip J, Braithwaite Antony W, Chircop Megan, ’The Dynamin inhibitors MiTMAB and OcTMAB induce Cytokinesis failure and inhibit cell proliferation in human cancer cells’, Molecular Cancer Therapeutics, 9 1995-2006 (2010) [C1]

Odell Luke, Howan Dian, Gordon Christopher Peter, Robertson Mark James, Chau Ngoc, Mariana Anna, Whiting Ainslie E, Abagyan Ruben, Daniel James A, Gorgani Nick N, Robinson Phillip J, McCluskey Adam, ’The Pthaladyns: GTP competitive inhibitors of Dynamin I and II GTPase derived from virtual screening’, Journal of Medicinal Chemistry, 53 5267-5280 (2010) [C1]

Bajsa Joanna, McCluskey Adam, Gordon Christopher Peter, Stewart Scott Gordon, Hill Timothy Adrian, Sahu Rajnish, Duke Stephen O, Tekwani Babu L, ’The antiplasmodial activity of norcantharidin analogs’, Bioorganic & Medicinal Chemistry Letters, 20 6688-6695 (2010) [C1]

Mann Jason Peter, McCluskey Adam, Atkin Rob, ’Activity and thermal stability of lysozyme in alkylammonium formate ionic liquids: Influence of cation modification’, Green Chemistry, 11 785-792 (2009) [C1]

Odell Luke, Chau Ngoc, Mariana Anna, Graham Mark E, Robinson Phillip J, McCluskey Adam, ’Azido and diazarinyl analogues of bis-tyrphostin as asymmetrical inhibitors of dynamin GTPase’, Chemmedchem, 4 1182-1188 (2009) [C1]

Whitehead Jacqueline Afra, Zhang Jie, McCluskey Adam, Lawrance Geoffrey Alan, ’Comparative leaching of a sulfidic gold ore in ionic liquid and aqueous acid with thiourea and halides using Fe(III) or HSO5- oxidant’, Hydrometallurgy, 98 276-280 (2009) [C1]

Turner Nicholas William, Holmes Natalie Patricia, Brisbane Carrie Emma, McGeachie Andrew B, Bowyer Michael Christian, McCluskey Adam, Holdsworth Clovia Isabel, ’Effect of template on the formation of phase-inversed molecularly imprinted polymer thin films: An assessment’, Soft Matter, 5 3663-3671 (2009) [C1]

Hill Timothy Adrian, Gordon Christopher Peter, McGeachie Andrew B, Venn-Brown Barbara, Odell Luke, Chau Ngoc, Quan Annie, Mariana Anna, Sakoff Jennette A, Chircop Megan, Robinson Phillip J, McCluskey Adam, ’Inhibition of dynamin mediated endocytosis by the dynoles-synthesis and functional activity of a family of indoles’, Journal of Medicinal Chemistry, 52 3762-3773 (2009) [C1]

Holland Ian Paul, McCluskey Adam, Sakoff Jennette Anne, Gilbert Jayne, Chau Ngoc, Robinson Phillip J, Motti Cherie A, Wright Anthony D, Van Altena Ian Andrew, ’Steroids from an Australian Sponge Psammoclema sp’, Journal of Natural Products, 72 102-106 (2009) [C1]

Sauer Benjamin, Gilbert Jayne, Sakoff Jennette Anne, McCluskey Adam, ’Synthesis of 4-substituted-3-hydroxy-5-oxo-10-oxa-4-azatricyclo[5.2.1]dec-3-yl Acetic Acid Ethyl Esters as Norcantharidin Analogues’, Letters in Drug Design & Discovery, 6 1-7 (2009) [C1]

Zayas Hazit Alabata, Bowyer Michael Christian, Gordon Christopher Peter, Holdsworth Clovia Isabel, McCluskey Adam, ’Synthesis of biaryl-styrene monomers by microwave-assisted Suzuki coupling’, Tetrahedron Letters, 50 5894-5895 (2009) [C1]

Thaqi Ali, McCluskey Adam, Scott Janet L, ’A mild Boc deprotection and the importance of a free carboxylate’, Tetrahedron Letters, 49 6962-6964 (2008) [C1]

Zhang Jie, Lawrance Geoffrey Alan, Chau Ngoc, Robinson Phillip J, McCluskey Adam, ’From Spanish fly to room-temperature ionic liquids (RTILs): Synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs’, New Journal of Chemistry, 32 28-36 (2008) [C1]

Odell Luke, Skopec Jana, McCluskey Adam, ’Isolation and identification of unique marker compounds from the Tasmanian poppy Papaver somniferum N. Implications for the identification of illicit heroin of Tasmanian origin’, Forensic Science International, 175 202-208 (2008) [C1]

Hill Timothy Adrian, Stewart Scott Gordon, Gordon Christopher Peter, Ackland Stephen R, Gilbert Jayne, Sauer Benjamin, Sakoff Jenette A, McCluskey Adam, ’Norcantharidin analogues: Synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition’, ChemMedChem, 3 1878-1892 (2008) [C1]

Whitehead Jacqueline Afra, Zhang Jie, Pereira N, McCluskey Adam, Lawrance Geoffrey Alan, ’Application of 1-alkyl-3-methyl-imidazolium ionic liquids in the oxidative leaching of sulphidic copper, gold and silver ores’, Hydrometallurgy, 88 109-120 (2007) [C1]

Hemley C F, McCluskey Adam, Keller P A, ’Corticotropin releasing hormone - A GPCR drug target’, Current Drug Targets, 8 105-115 (2007) [C1]

Odell Luke, McCluskey Adam, Failes T W, Tiekink E R T, ’Crystal and molecular structures of benzyl-(2-chloro-6-methylpyrimidin-4-yl)amine and benzyl-(4-chloro-6-methylpyrimidin-2-yl)amine: Confirmation of computationally predicted restricted rotation’, Journal of Chemical Crystallography, 37 817-824 (2007) [C1]

Hill Timothy Adrian, Stewart Scott Gordon, Sauer Benjamin, Gilbert J, Ackland Stephen, Sakoff J A, McCluskey Adam, ’Heterocyclic substituted cantharidin and norcantharidin analogues-synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity’, Bioorganic and Medicinal Chemistry Letters, 17 3392-3397 (2007) [C1]

McCluskey Adam, Holdsworth Clovia Isabel, Bowyer Michael Christian, ’Molecularly imprinted polymers (MIPs): sensing, an explosive new opportunity?’, Organic & Biomolecular Chemistry, 5 3233-3244 (2007) [C1]

Booker Katherine Marie, Bowyer Michael Christian, Lennard C J, Holdsworth Clovia Isabel, McCluskey Adam, ’Molecularly imprinted polymers and room temperature ionic liquids: Impact of template on polymer morphology’, Australian Journal of Chemistry, 60 51-56 (2007) [C1]

Quan Annie, McGeachie Andrew B, Keating Damien J, Van Dam Ellen M, Rusak Jenny, Chau Ngoc, Malladi Chandra S, Chen Chen, McCluskey Adam, Cousin Michael A, Robinson Phillip J, ’Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II’, Molecular Pharmacology, 72 1425-1439 (2007) [C1]

Qi Ying, Evans I, McCluskey Adam, ’New impurity profiles of recent Australian imported 'ice': Methamphetamine impurity profiling and the identification of (pseudo)ephedrine and Leuckart specific marker compounds’, Forensic Science International, 169 173-180 (2007) [C1]

Hill Timothy Adrian, Stewart Scott Gordon, Ackland Stephen, Gilbert J, Sauer Benjamin, Sakoff Jennette Anne, McCluskey Adam, ’Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation’, Bioorganic and Medicinal Chemistry, 15 6126-6134 (2007) [C1]

Stewart Scott Gordon, Hill Timothy Adrian, Gilbert Jayne, Ackland Stephen, Sakoff Jennette A, McCluskey Adam, ’Synthesis and biological evaluation of norcantharidin analogues: Towards PP1 selectivity’, Bioorganic and Medicinal Chemistry, 15 7301-7310 (2007) [C1]

Odell Luke, Skopec Jana, McCluskey Adam, ’A `cold synthesis' of heroin and implications in heroin signature analysis: Utility of trifluoroacetic/acetic anhydride in the acetylation of morphine’, Forensic Science International, 164 221-229 (2006) [C1]

Qi Ying, Evans Ian D, McCluskey Adam, ’Australian Federal Police seizures of illicit crystalline methamphetamine (`ice') 1998-2002: Impurity analysis’, Forensic Science International, 164 201-210 (2006) [C1]

Booker Katherine Marie, Bowyer Michael Christian, Holdsworth Clovia Isabel, McCluskey Adam, ’Efficient preparation and improved sensitivity of molecularly imprinted polymers using room temperature ionic liquids’, Chemical Communications 1730-1732 (2006) [C1]

Griffith Renate, Brown Michael Nicholas, McCluskey Adam, Ashman Leonie Kay, ’Small molecule inhibitors of protein kinases in cancer - How to overcome resistance’, Mini-Reviews in Medicinal Chemistry, 6 1101-1110 (2006) [C1]

Schwarz Lachlan John, Bowyer Michael Christian, Holdsworth Clovia Isabel, McCluskey Adam, ’Synthesis and evaluation of a molecularly imprinted polymer selective to 2,4,6-trichloroanisole’, Australian Journal of Chemistry, 59 129-134 (2006) [C1]

Keller P A, McCluskey Adam, Morgan J, O'Connor S M J, ’The role of the HPA axis in psychiatric disorders and CRF antagonists as potential treatments’, Archiv Der Pharmazie, 339 346-355 (2006) [C1]

McCluskey Adam, Leitch Sarah Kathleen, Garner James Andrew, Caden Christine E, Hill Timothy Adrian, Odell Luke, Stewart Scott Gordon, ’BiCl3-mediated opening of epoxides, a facile route to chlorohydrins or amino alcohols: one reagent, two paths’, Tetrahedron Letters, 46 8229-8232 (2005) [C1]

Holdsworth Clovia Isabel, Bowyer Michael Christian, Lennard C, McCluskey Adam, ’Formulation of cocaine-imprinted polymers utilizing molecular modelling and NMR analysis’, Australian Journal of Chemistry, 58 315-320 (2005) [C1]

Hill Timothy Adrian, Sakoff J A, Robinson P J, McCluskey Adam, ’Parallel solution-phase synthesis of targeted tyrphostin libraries with anticancer activity’, Australian Journal of Chemistry, 58 94-103 (2005) [C1]

Leitch Sarah Kathleen, Addison-Jones Jennifer, McCluskey Adam, ’Regioselective N- and C2-electrophilic substitution of 3-substituted indoles (short communication)’, Tetrahedron Letters, 46 2915-2918 (2005) [C1]

Hill Timothy Adrian, Odell Luke, Edwards Jennifer Kate, Graham M E, McGeachie A B, Rusak J, Quan A, Abagyan R, Scott J L, Robinson P J, McCluskey Adam, ’Small molecule inhibitors of dynamin I GTPase activity: Development of dimeric tyrphostins’, Journal of Medicinal Chemistry, 48 7781-7788 (2005) [C1]

Whitehead Jacqueline Afra, Lawrance Geoffrey Alan, McCluskey Adam, ’'Green' leaching: recyclable and selective leaching of gold-bearing ore in an ionic liquid’, Green Chemistry, 6 313-315 (2004) [C1]

Whitehead Jacqueline Afra, Lawrance Geoffrey Alan, McCluskey Adam, ’Analysis of Gold in Solutions Containing Ionic Liquids by Inductively Coupled Plasma Atomic Emission Spectometry’, Australian Journal of Chemistry, 57 151-155 (2004) [C1]

Garner James Andrew, Keller Paul A, McCluskey Adam, ’Corticotrophin Releasing Hormone: Chemistry and Recent Developments’, Australian Journal of Chemistry, 57 393-407 (2004) [C1]

Garner James Andrew, Hill Timothy Adrian, Odell Luke, Keller Paul, Morgan Jody, McCluskey Adam, ’Identification of Aminopyrimidine Regioisomers via Line Broadening Effects in 1H and 13C NMR Spectroscopy’, Australian Journal of Chemistry, 57 1079-1083 (2004) [C1]

Bowyer Michael Christian, Gordon Charles M, Leitch Sarah Kathleen, McCluskey Adam, Ritchie Craig, ’Indium-Mediated Addition of 4-Bromocrotonic Acid to Aldehydes and Ketones - A Simple, High Yielding Route to Alpha-Allyl-Beta-Hydroxy Carboxylic Acids’, Australian Journal of Chemistry: an international journal for chemical science, 57 135-137 (2004) [C1]

Hill Timothy Adrian, Odell Luke, Quan Annie, Abagyan Ruben, Ferguson Gemma Natasha, Robinson Phillip J, McCluskey Adam, ’Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity’, Bioorganic & Medicinal Chemistry Letters, 14 3275-3278 (2004) [C1]

Hart Matthew E, Chamberlin A Richard, Walkom Cecilia Clare, Sakoff Jeanette A, McCluskey Adam, ’Modified norcantharidins: synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity’, Bioorganic & Medicinal Chemistry Letters, 14 1969-1973 (2004) [C1]

Sakoff Jeannette A, McCluskey Adam, ’Protein Phosphatase Inhibition: Structure Based Design. Towards New Therapeutic Agents’, Current Pharmaceutical Design, 10 1139-1159 (2004) [C1]

Sakoff Jennette Anne, Howitt I J, Ackland Stephen, McCluskey Adam, ’Serine/threonine protein phosphatase inhibition enhances the effect of thymidylate synthase inhibition’, Cancer Chemotherapy and Pharmacology, 53 225-232 (2004) [C1]

Schwarz Lachlan John, Holdsworth Clovia Isabel, McCluskey Adam, Bowyer Michael Christian, ’Synthesis and Evaluation of a Molecularly Imprinted Polymer Selective to 2,4,6-Trichlorophenol’, Australian Journal of Chemistry, 57 759-764 (2004) [C1]

McCluskey Adam, Bowyer Michael Christian, ’Synthetic antibodies and the Australian wine industry: A Hunter Valley solution to cork taint?’, Australian & New Zealand Grapegrower & Winemaker, 2004 111-115 (2004) [C3]

Leitch Sarah Kathleen, McCluskey Adam, ’A High Yielding One-Pot Synthesis of Allylic-Vinylic Alcohols: The Adducts of Tetraallylstannane and a,?-Unsaturated Carbonyl Compounds’, Synlett, - 699-701 (2003) [C1]

Correa W, Edwards J, McCluskey Adam, McKinnon I, Scott J L, ’A thermodynamic investigation of solvent-free reactions’, Green Chemistry, 5 30-33 (2003) [C1]

McCluskey Adam, Ackland Stephen, Bowyer Michael Christian, Baldwin Monique Louise, Garner James Andrew, Walkom Cecilia Clare, Sakoff Jennette Anne, ’Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines’, Bioorganic Chemistry, 31 66-77 (2003) [C1]

McCluskey Adam, Keller P A, Morgan J, Garner James Andrew, ’Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists’, Organic and Biomolecular Chemistry, 1 3353-3361 (2003) [C1]

Sakoff Ja, Ackland Sp, Baldwin Monique Louise, Atherton Mirella Anne, McCluskey Adam, ’Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues’, Investigational New Drugs, 20 1-11 (2002) [C1]

McCluskey Adam, Robinson Pj, Hill Timothy Adrian, Scott Jl, Edwards Jennifer Kate, ’Green chemistry approaches to the Knoevenagel condensation: comparison of ethanol, water and solvent free (dry grind) approaches’, Tetrahedron Letters, 43 3117-3120 (2002) [C1]

McCluskey Adam, Sim Atr, Sakoff Ja, ’Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies’, Journal of Medicinal Chemistry, 45 1151-1175 (2002) [C1]

Judeh Zma, Ching Cb, Bu J, McCluskey Adam, ’The first Bischler-Napieralski cyclization in a room temperature ionic liquid’, Tetrahedron Letters, 43 5089-5091 (2002) [C1]

McCluskey Adam, Atherton Mirella Anne, Walkom Cecilia Clare, Bowyer Mc, Sim Atr, Young Dj, Sakoff Ja, ’The first two cantharidin analogues displaying PP1 selectivity’, Bioorganic & Medicinal Chemistry Letters, 12 391-393 (2002) [C1]

McCluskey Adam, Ackland Sp, Gardiner E, Walkom Cecilia Clare, Sakoff Ja, ’The inhibition of protein phosphatases 1 and 2A: a new target for rational anti-cancer drug design?’, Anti-Cancer Drug Design, 16 291-303 (2002) [C1]

McCluskey Adam, Muderawan I W, Muntari, Young D J, ’A highly atom efficient, solvent promoted addition of tetraallylic, tetraallenic and tetrapropargylic stannanes to carbonyl compounds’, Journal of Organic chemistry, 66 7811-7817 (2001) [C1]

Lengyel I, Nairn A C, McCluskey Adam, Toth G, Penke B, Rostas J A P, ’Auto-inhibition of Ca2+/calmodulin-dependent protein kinase II by its ATP-binding domain’, Journal of Neurochemistry, 76 1066-1072 (2001) [C1]

McCluskey Adam, Walkom Cecilia Clare, Bowyer M C, Ackland S P, Gardiner E, Sakoff Jennette Anne, ’Cantharimides: A new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A’, Bioorganic & Medicinal Chemistry Letters, 11 2941-2946 (2001) [C1]

McCluskey Adam, Finn M, Bowman Maria, Keller P A, Smith Roger, ’2,7-dimethylthiazolo[4,5-d] pyradazine-4-(5H)-thione: a corticotrophin releasing hormone type 1 receptor agonist’, Australian journal of chemistry 905-8 (2000) [C1]

McCluskey Adam, Finn M, Bowman M, Keller Pa, Smith R, ’3,5-Dimethyl-7-hydrazinothiazolo[4,5-d]pyradazine-7-thiol: A corticotrophin releasing hormone type 1 receptor agonist’, Australian Journal of Chemistry, 53 905-908 (2000) [C1]

McCluskey Adam, Bowyer Mc, Collins E, Sim Atr, Sakoff Jennette Anne, Baldwin Monique Louise, ’Anhydride Modified Cantharidin Analogues: Synthesis, Inhibition of Protein Phosphatase 1 and 2A and Anti-Cancer Activity’, Bioorganic and Medicinal Chemistry Letters, 10 1687-1690 (2000) [C1]

McCluskey Adam, Atherton Mirella Anne, Mudgee Lm, Sim Atr, Sakoff Jennette Anne, Quinn Rj, ’Anhydride modified cantharidin analogues. Is ring opening important in the inhibition of protein phosphatase 2A?’, European Journal of Medicinal Chemistry, 35 957-964 (2000) [C1]

McCluskey Adam, Elfick Lynette Glenyce, Morgan J, Garner James Andrew, Keller Pa, ’Corticotropin releasing hormone: Therapeutic implications and medicinal chemistry developments’, Bioorganic and Medicinal Chemistry., 8 1213-1223 (2000) [C1]

McCluskey Adam, Garner James Andrew, Caballero S, Young Dj, ’Tetraallylstannane and Weinreb amides: a simple 'green' route to N-protected homoallylic alcohols and allyl ketones’, Tetrahedron Letters, 41 8147-8151 (2000) [C1]

McCluskey Adam, Garner James Andrew, ’Garner, J, McCluskey, A, "A simple, expedient synthesis of substituted pyrimidines: Aminolysis of dichloropyrimidines in the presence of LiClO4’, Heterocyclic Communications, 5 503 ? 508 (1999) [C1]

McCluskey Adam, Gordon Cm, ’Ionic Liquids: c convenient solvent for environmentally friendly allylation reactions with tetraallylstannane’, Chemical Communications, 1999 1431 - 1432 (1999) [C1]

McCluskey Adam, Gordon Cm, ’Ionic liquids a convenient solvent for environmentally friendly allylation reactions with tetraallylstannane’, Chemical Communications, 1999 1431-1432 (1999) [C1]

Gordon C M, McCluskey Adam, ’Ionic liquids: a convenient solvent for environmentally friendly allylation reactions with tetraallylstannane’, Chemical Communications, -- 1431-1432 (1999) [C1]

McCluskey Adam, Keller Pk, Bowman M, Dang Kh, Garner James Andrew, Leach Sp, Smith R, ’Pharmacophore Development for Corticotrophin-Releasing Hormone: New Insights into Inhibitor Activity’, Journal Of Medicinal Chemistry, 42 2351 - 2357 (1999) [C1]

McCluskey Adam, Garner James Andrew, Smith R, Leach Sp, Dang Dh, Bowman M, Keller Pa, ’Pharmacophore development for corticotrophin releasing hormone; new insights into inhibitor activity’, Journal of Medicinal Chemistry, 42 2351 ? 2357 (1999) [C1]

Keller P A, Bowman M, Dang K H, Garner James Andrew, Leach S P, Smith R, McCluskey Adam, ’Pharmacophore development for corticotropin-releasing hormone: new insights into inhibitor activity’, Journal of Medicinal Chemistry, 42, No. 13 2351-2357 (1999) [C1]

Garner James Andrew, McCluskey Adam, ’Regiocontrolled amination of dichloropyrimidines in LiC104-Et20 solutions’, Heterocyclic Communications, 5, No. 6 503-508 (1999) [C1]

McCluskey Adam, ’The allylation of carbonyl (and acetal) compounds by tetraallylstannane’, Green Chemistry, -- 167-168 (1999) [C1]

McCluskey Adam, ’Water organic chemistry: The allylation of carbonyl (and acetal) compounds by tetraallylstannane’, Green Chemistry, 1 167 - 168 (1999) [C1]

McCluskey Adam, ’Water promoted organic chemistry. The allylation of carbonyl (and acetal) compounds by tetraallylstannane’, Green Chemistry, 1 161-162 (1999) [C1]

McCluskey Adam, Ying L, Camp D, Moni Rw, Quinn Rj, ’Diimidazo[1,2-C;4',5'-E] Pyrimidines N6-N1 Conformationally Restricted Andenosines’, Bioorganic and Medicinal Chemistry Letters, 8 695-698 (1998) [C1]

McCluskey Adam, Wayan Muderawan I, Muntari J, Young Dj, ’Solvent Assisted Addition of Tetraallylic, Tetraallenic and Tetraaproparagylic Stannanes to Aldehydes and Acetals’, SynLett, -- 909-912 (1998) [C1]

McCluskey Adam, Dunkin Ir, ’Tetrachlorocyclopentadienone O-oxide, A Facile Oxygen Transfer Reagent, Further Evidence for the Disproportionation of Cycloalkoky Radicals’, Bulletin of the Chemical Society of Japan, 71 1397-1400 (1998) [C1]

Chapter in Book

McCluskey Adam, Lawrance Geoffrey Alan, Leitch Sarah Kathleen, Owen Michael Paul, Hamilton Ian Campton, ’Ionic liquids and metal ions: from green chemistry to ore refining’, Ionic Liquids: Industrial applications to green chemistry, American Chemical Society, Washington DC, USA, 199-214 (2002) [B1]

Review

Keller P A, Kirkwood Kristie Lee, Morgan J, Westcott S, McCluskey Adam, ’The prevention of preterm labour - corticotrophin releasing hormone type 1 receptors as a target for drug design and development’, Med. Chem. (2003) [D3]

Conference Publication

Gunning P W, Hook J, Schevzov G, Desouza M, Creed S, McCluskey Adam, Hardemann E C, Dixon I, Stehn J, ’Actin filaments containing tropomyosin Tm5NM1/2 perform essential functions as revealed by gene knockouts and anti-Tm drugs’, The American Society for Cell Biology 50th Annual Meeting Abstracts, Phildelphia, PA (2010) [E3]

Joshi Sanket, Gaddipatti Swetha, Gilbert Jayne, Smith Charlotte M, Gordon Christopher Peter, Sakoff Jennette Anne, McCluskey Adam, Robinson Phillip J, Braithwaite Antony W, Chircop Megan, ’Dynamin inhibition: A new therapeutic approach for the treatment of cancer’, AACR 101st Annual Meeting 2010. Abstracts, Washington, DC (2010) [E3]

Chircop M, Perera S, Ma M P C, Lau H, Gilbert J, Jones N C, Dabacco G, Gordon Christopher Peter, Young K A, Morokoff A, Sakoff Jennette Anne, O'Brien T, McCluskey Adam, Robinson P J, ’Dynole 34-2 is a potent inhibitor of dynamin that induces cell death following cytokinesis failure and suppresses glioblastoma tumour growth in vivo’, OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Australia (2010) [E3]

McCluskey Adam, Robinson Phillip J, ’From dyngoes to dynasores: Selective dynamin inhibitors as novel antiepileptic agents’, Australasian Society of Clinical and Experimental Pharmacology and Toxicology (ASCEPT) Annual Scientific Meeting, Melbourne, Vic (2010) [E3]

Bonello T, Stehn J, Schevzov G, Coombes J, McCluskey Adam, Haass N, Dixon I, Gunning P, ’Targeting the tropomyosin isoform TM5NM1 impairs tumour survival, proliferation and migration’, OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Australia (2010) [E3]

Mariana A, Hill T A, McGeachie A B, Chau N, Daniel J A, Gorgani N N, McCluskey Adam, Robinson P J, ’Towards isoform-selective dynamin inhibitors’, OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Australia (2010) [E3]

Stehn J, Schevzov G, Bonello T, McCluskey Adam, Haass N, Palmer S, Hardeman E, Allanson M, Reeve V, Gunning P, ’Tropomyosin Tm5NM1: A novel target for cancer therapy’, EJC Supplements, Berlin, Germany (2010) [E3]

Robinson P J, McCluskey Adam, ’Dynamin inhibitors reduce synaptic transmission and are novel anti-epileptic drugs’, Journal of Neurochemistry, Beijing, China (2009) [E3]

Bajsa J, Sahu R, McCluskey Adam, Duke S O, Tekwani B L, ’Antimalarial activity of cantharidin analogs: potential serine/threonine protein phosphatase inhibitors’, Planta Medica, Oxford, MI (2008) [E3]

Wright A, McCluskey Adam, Macgregor K, Guenther J, ’Potential ecological role, chemistry and molecular modelling studies of secondary metabolites isolated from the tropical marine sponge Cymbastela hooperi’, Planta Medica, Athens, Greece (2008) [E3]

McGeachie A B, Odell Luke, Hill Timothy Adrian, Quan A, Chau N, Graham Mark Evan, McCluskey Adam, Robinson Phillip James, ’Analogues of Bis-T-22 potently inhibit endocytosis (Poster)’, 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]

Quan A, McGeachie A B, Van Dam E M, Chau N, McCluskey Adam, Cousin M A, Robinson Phillip James, ’Mitmab is a surface-active dynamin inhibitor that blocks dynamin i or dynamin ii mediated endocytosis (Poster)’, 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]

Chau N, Quan A, Hill Timothy Adrian, McCluskey Adam, Robinson P J, ’The apparent potency of dynamin GTPase inhibitors is dependent on dynamin concentration: a new colorimetric assay (Poster)’, 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]

Stehn Justin R, Butler Tanya, Winlaw David, McCluskey Adam, Gunning Peter, ’Tropomyosin containing actin filaments as cancer-specific targets’, AACR Meeting Abstracts Online (Abstracts of the 98th AACR Annual Meeting), Los Angeles (2007) [E3]

Patent

McCluskey Adam, Robinson Phillip James, Hill Timothy Adrian, Methods and agents for inhibiting dynamic-dependent endocytosis (2005) [I1]

Skills

Key Words

Countries

Return to Search page