The University of Newcastle, Researcher report.

Researcher: Doctor Mark Baker
School: School of Environmental and Life Sciences
Personal URL:

Funded Projects

Please note, only grants administered through the University of Newcastle Research Office are recorded here. For a more complete picture of the researcher's grant history a Personal URL may be supplied, above.

Research Team Initial Year Duration (Years) Funding Body/Client Award Type Title of Project Collaborating Partners Total Cash $ Total Inkind $
Doctor Mark Baker 2012 4 National Health & Medical Research Council Career Development Fellowships Understanding sperm motility for infertility and contraceptive purposes   432568  
Laureate Professor Robert Aitken;Professor Eileen McLaughlin;Ms Belinda Nixon;Doctor Shaun Roman;Doctor Mark Baker;Doctor Geoffry De Iuliis;Doctor Lisa Mitchell;Doctor Matthew Jobling 2012 1 National Health & Medical Research Council Equipment Grant BMG SPECTROstar Nano   15000  
Doctor Mark Baker;Laureate Professor Robert Aitken 2011 1 University of Newcastle Equipment Grant 3D Ion Trap Mass Spectrometer with ETD for Top Down Proteomics Applications   170000  
Doctor Mark Baker;Laureate Professor Robert Aitken;Professor Roger Smith;Professor Keith Jones;Professor Raymond Rose;Professor Lois Salamonsen 2011 1 Prince Henry's Institute of Medical Research Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding An Advanced Mass Spectrometer for Applications in Phospho-Proteomics, Glycomics and Top-Down Sequencing of Proteins   15000  
Doctor Mark Baker;Laureate Professor Robert Aitken;Professor Roger Smith;Professor Keith Jones;Professor Raymond Rose;Professor Lois Salamonsen 2011 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) An Advanced Mass Spectrometer for Applications in Phospho-Proteomics, Glycomics and Top-Down Sequencing of Proteins   250000  
Doctor Mark Baker 2011 3 National Health & Medical Research Council Project Grant Understanding the Molecular Basis of Epididymal Maturation: How Does the Epididymis Modify Spermatozoa, Allowing them to Recognise the Egg?   565222  
Laureate Professor Robert Aitken;Doctor Mark Baker;Professor Kenneth Beagley;Professor Adam McCluskey 2011 3 Australian Research Council Discovery Projects Chemical principles underpinning a spermostatic-microbiostatic agent capable of preventing pregnancy and the spread of sexually transmitted disease   735000  
Professor Adam McCluskey;Laureate Professor Robert Aitken;Professor Paul Dastoor;Professor Phillip Robinson;Professor Eileen McLaughlin;Emeritus Professor Geoffrey Lawrance;Associate Professor Marcel Maeder;Associate Professor Richard Dunstan;Doctor Shaun Roman;Doctor Rob Atkin;Doctor Clovia Holdsworth;Doctor Mark Baker;Doctor Nicole Verrills;Professor Gottfried Otting;Associate Professor Brett Nixon;Doctor Xiaojing Zhou;Ms Megan Chircop;Doctor Warwick Belcher 2010 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry   500000  
Professor Adam McCluskey;Laureate Professor Robert Aitken;Professor Paul Dastoor;Professor Phillip Robinson;Professor Eileen McLaughlin;Emeritus Professor Geoffrey Lawrance;Associate Professor Marcel Maeder;Associate Professor Richard Dunstan;Doctor Shaun Roman;Doctor Rob Atkin;Doctor Clovia Holdsworth;Doctor Mark Baker;Doctor Nicole Verrills;Professor Gottfried Otting;Associate Professor Brett Nixon;Doctor Xiaojing Zhou;Ms Megan Chircop;Doctor Warwick Belcher 2010 1 University of Newcastle Equipment Grant An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry   280000  
Doctor Mark Baker;Professor Adam McCluskey 2010 1 Hunter Children`s Research Foundation Research Grant The design of novel, affinity-based technology to specifically isolate phosphotyrosine-containing pedtides   25000  
Doctor Mark Baker 2010 1 University of Newcastle Award for Research Excellence 2009 FSIT Award for Research Excellence   2000  
Doctor Mark Baker;Laureate Professor Robert Aitken;Professor Adam McCluskey;Associate Professor Brett Nixon;Professor John Rostas;Professor Eileen McLaughlin 2010 1 National Health & Medical Research Council Equipment Grant Waters, Ultra high performance liquid chromatography system (nano-Aquity)   30000  
Conjoint Professor Christopher Levi;Doctor Mark Baker;Doctor Neil Spratt;Professor John Rostas 2009 1 NSW Office for Science & Medical Research China-NSW Collaborative Research Program China-Australia therapeutic hypothermia in stroke (CATHS) research program: identification of diagnostic molecular markers and therapeutic targets involved in re-warming related brain injury   230275  
Laureate Professor Robert Aitken;Professor Adam McCluskey;Doctor Mark Baker;Doctor Nicole Verrills;Associate Professor Marcel Maeder;Doctor Xiaojing Zhou;Professor Eileen McLaughlin;Associate Professor Brett Nixon;Doctor Shaun Roman;Professor Raymond Rose;Associate Professor Richard Dunstan;Professor Christopher Grof;Professor Roger Smith;Conjoint Professor Peter Gibson;Conjoint Professor Alison Jones;Professor Michael Calford;Professor Keith Jones;Doctor Rick Thorne;Emeritus Professor Peter Dunkley;Professor Paul Foster;Conjoint Professor Leonie Ashman;Professor Gordon Burns;Associate Professor Phillip Dickson;Professor John Rostas;Professor Rodney Scott;Doctor Paul Tooney;Professor Philip Hansbro;Professor Pablo Moscato;Professor Paul Dastoor;Associate Professor Peter Lewis 2009 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry   50000  
Laureate Professor Robert Aitken;Professor Adam McCluskey;Doctor Mark Baker;Doctor Nicole Verrills;Associate Professor Marcel Maeder;Doctor Xiaojing Zhou;Professor Eileen McLaughlin;Associate Professor Brett Nixon;Doctor Shaun Roman;Professor Raymond Rose;Associate Professor Richard Dunstan;Professor Christopher Grof;Professor Roger Smith;Conjoint Professor Peter Gibson;Conjoint Professor Alison Jones;Professor Michael Calford;Professor Keith Jones;Doctor Rick Thorne;Emeritus Professor Peter Dunkley;Professor Paul Foster;Conjoint Professor Leonie Ashman;Professor Gordon Burns;Associate Professor Phillip Dickson;Professor John Rostas;Professor Rodney Scott;Doctor Paul Tooney;Professor Philip Hansbro;Professor Pablo Moscato;Professor Paul Dastoor;Associate Professor Peter Lewis 2009 1 Australian Research Council Linkage Infrastructure Equipment & Facilities (LIEF) An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry   495000  
Laureate Professor Robert Aitken;Doctor Mark Baker 2009 1 Contraceptive Research and Development Program Development of New or Improved Contraceptive Products Assessing the significance of the sperm thioredoxins as contraceptive targets for the male   148096  
Doctor Mark Baker 2009 3 National Health & Medical Research Council Project Grant Identification and characterisation of phosphorylation events taking place during human sperm capacitation   269250  
Doctor Mark Baker 2008 1 Hunter Medical Research Institute PULSE Education Prize PULSE Education Prize   4000  
Laureate Professor Robert Aitken;Doctor Mark Baker 2007 1 Schering AG Research Networks AMPPAII Proposal for completion of the Sptrx KO mice study   198741  
Doctor Mark Baker 2007 1 University of Newcastle Fellowship Grant 2007 Research Fellowship Project Grant   15000  
Doctor Mark Baker 2007 5 University of Newcastle Research Fellowship 2007 Research Fellowship   491270  

Research Publications

Please note, the publications listed here:
(1) relate to the researcher's position at the University of Newcastle only
(2) are for selected categories of publications, and
(3) relate to publication year 1998, onwards.
For a more complete picture of the researcher's publication history a Personal URL may be supplied at the top of this page.

Journal Article

Baker Mark Andrew, ’The ‘omics revolution and our understanding of sperm cell biology’, Asian Journal of Andrology, 13 6-10 (2011) [C1]

Baker Mark Andrew, Reeves Gabi Monika, Hetherington Louise, Aitken Robert John, ’Analysis of proteomic changes associated with sperm capacitation through the combined use of IPG-strip pre-fractionation followed by RP chromatography LC-MS/MS analysis’, Proteomics, 10 482-495 (2010) [C1]

Baker Mark Andrew, Smith Nathan Druery, Hetherington Louise, Taubman Kristy, Graham Mark E, Robinson Phillip J, Aitken Robert John, ’Label-free quantitation of phosphopeptide changes during rat sperm capacitation’, Journal of Proteome Research, 9 718-729 (2010) [C1]

Ewen Katherine Amme, Baker Mark Andrew, Wilhelm Dagmar, Aitken Robert John, Koopman Peter, ’Global survey of protein expression during gonadal sex determination in mice’, Molecular & Cellular Proteomics, 8 2624-2641 (2009) [C1]

Baker Mark Andrew, Hetherington Louise, Curry Benjamin John, Aitken Robert John, ’Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa: Its implications during capacitation’, Developmental Biology, 333 57-66 (2009) [C1]

Baker Mark Andrew, Aitken Robert John, ’Proteomic insights into spermatozoa: Critiques, comments and concerns’, Expert Review of Proteomics, 6 691-705 (2009) [C1]

Aitken Robert John, Baker Mark Andrew, Doncel Gustavo F, Matzuk Martin M, Mauck Christine K, Harper Michael J K, ’As the world grows: Contraception in the 21st century’, Journal of Clinical Investigation, 118 1330-1343 (2008) [C1]

Aitken Robert John, Hughes Louise Mary, Griffith Renate, Baker Mark Andrew, ’Bridging the gap between male and female fertility control; contraception-on-demand’, Contraception, 78 S28-S35 (2008) [C1]

Mitchell Lisa Ann, Nixon Brett, Baker Mark Andrew, Aitken Robert John, ’Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa’, Molecular Human Reproduction, 14 235-243 (2008) [C1]

Baker Mark Andrew, Hetherington Louise, Reeves Gabi Monika, Aitken Robert John, ’The mouse sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification’, Proteomics, 8 1720-1730 (2008) [C1]

Baker Mark Andrew, Hetherington Louise, Reeves Gabi Monika, Muller Jorg, Aitken Robert John, ’The rat sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification’, Proteomics, 8 2312-2321 (2008) [C1]

Aitken Robert John, Baker Mark Andrew, ’The role of proteomics in understanding sperm cell biology’, International Journal of Andrology, 31 295-302 (2008) [C1]

Baker Mark Andrew, Reeves Glenn E, Hetherington Louise, Muller J, Baur I, Aitken Robert John, ’Identification of gene products present in Triton X-100 soluble and insoluble fractions of human spermatozoa lysates using LC-MS/MS analysis’, Proteomics Clinical Applications, 1 524-532 (2007) [C1]

Aitken Robert John, Nixon Brett, Lin Minjie, Koppers Adam John, Lee Yun Hwa, Baker Mark Andrew, ’Proteomic changes in mammalian spermatozoa during epididymal maturation’, Asian Journal of Andrology, 9 554-564 (2007) [C1]

Aitken Robert John, Baker Mark Andrew, ’The role of proteomics in understanding sperm cell biology’, International Journal of Andrology, 30 1-8 (2007) [C1]

Baker Mark Andrew, Hetherington Louise, Aitken Robert John, ’Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa’, Journal of Cell Science, 119 3182-3192 (2006) [C1]

Lin Minjie, Lee Yun Hwa, Xu Weiran, Baker Mark Andrew, Aitken Robert John, ’Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse’, Biology of Reproduction, 75 588-597 (2006) [C1]

Aitken Robert John, Baker Mark Andrew, ’Oxidative stress, sperm survival and fertility control’, Molecular and Cellular Endocrinology, 250 66-69 (2006) [C1]

Baker Mark Andrew, Krutskikh Anton, Curry Benjamin John, Hetherington Louise, Aitken Robert John, ’Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa’, Biology of Reproduction, 73 334-342 (2005) [C1]

Baker Mark Andrew, Witherdin Roxanne Frances, Hetherington Louise, Cunningham Kelly Anne, Aitken Robert John, ’Identification of post-translational modifications that occur during sperm maturation using difference in two-dimensional gel electrophoresis’, Proteomics, 5 1003-1012 (2005) [C1]

Baker Mark Andrew, Aitken Robert John, ’Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility’, Reproductive Biology and Endocrinology, 3 9 (2005) [C1]

Sidhu K S, Mate Karen Elizabeth, Gunasekera T, Veal D, Hetherington Louise, Baker Mark Andrew, Aitken Robert John, Rodger John Cameron, ’A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula)’, Reproduction, 127 95-103 (2004) [C1]

Baker Mark Andrew, Hetherington Louise, Ecroyd Heath William, Roman Shaun Daryl, Aitken Robert John, ’Analysis of the mechanism by which calcium negatively regulates the tyrosine phoshorylation cascade associated with sperm capacitation’, Journal of Cell Science, 117 211-222 (2004) [C1]

Baker Mark Andrew, Krutskikh Anton, Curry Benjamin John, McLaughlin Eileen Anne, Aitken Robert John, ’Identification of Cytochrome P450-Reductase as the Enzyme Responsible for NADPH-Dependent Lucigenin and Tetrazolium Salt Reduction in Rat Epididymal Sperm Preparations’, Biology of Reproduction, 71 307-318 (2004) [C1]

Aitken Robert John, Baker Mark Andrew, ’Oxidative stress and male reproductive biology’, Reproduction, Fertility and Development, 16 581-588 (2004) [C1]

Aitken Robert John, Ryan Angela Louise, Baker Mark Andrew, McLaughlin Eileen Anne, ’Redox activity associated with the maturation and capacitation of mammalian spermatozoa’, Free Radical Biology and Medicine, 36 994-1010 (2004) [C1]

Aitken Robert John, Baker Mark Andrew, O'Bryan Moira, ’Shedding Light on Chemiluminescence: The Application of Chemiluminescence in Diagnostic Andrology’, Journal of Andrology, 25 455-465 (2004) [C1]

Baker Mark Andrew, Aitken Robert John, ’The importance of redox regulated pathways in sperm cell biology’, Molecular and Cellular Endocrinology, 216 47-54 (2004) [C1]

Baker Mark Andrew, Krutskikh Anton, Aitken Robert John, ’Biochemical entities involved in reactive oxygen species generation by human spermatozoa’, Protoplasma 145-151 (2003) [C1]

Baker Mark Andrew, Lewis Beverley, Hetherington Louise, Aitken Robert John, ’Development of the Signalling Pathways Associated With Sperm Capacitation During Epididymal Maturation’, Molecular Reproduction and Development 446-457 (2003) [C1]

Aitken Robert John, Ryan Angela Louise, Curry Benjamin John, Baker Mark Andrew, ’Multiple forms of redox activity in populations of human spermatozoa’, Molecular Human Reproduction, 9 645-661 (2003) [C1]

Aitken Robert John, Baker Mark Andrew, Sawyer Dennis Earl, ’Oxidative stress in the male germ line and its role in the aetiology of male infertility and genetic disease’, Reproductive BioMedicine, 7 65-70 (2003) [C1]

Aitken Robert John, Baker Mark Andrew, ’Reactive oxygen species generation by human spermatozoa: a continuing enigma’, International Journal of Andrology, 25 191-194 (2002) [C1]

Chapter in Book

Aitken Robert John, Baker Mark Andrew, De Iuliis Geoffry Nunzio, Nixon Brett, ’New insights into sperm physiology and pathology’, Fertility Control, Springer, Berlin, 99-115 (2010) [B1]

Aitken Robert John, Roman Shaun Daryl, Baker Mark Andrew, De Iuliis Geoffry Nunzio, ’Redox regulation of DNA damage in the male germ line’, Male-Mediated Developmental Toxicity, Royal Society of Chemistry, London, United Kingdom, 197-209 (2007) [B1]

Conference Publication

Baker Mark Andrew, Hetherington Louise, Reeves Gabi Monika, Smith Nathan Druery, Aitken Robert John, ’Comparative and phospho proteomics: Identification of protein changes during sperm maturation’, Proceedings of 41st Annual Meeting of the Society for the Study of Reproduction. "Reproductive Biology: Basic Discoveries that Affect Our Lives", Kailua-Kona, Hawaii (2008) [E3]

Baker Mark Andrew, ’The proteomic analysis of sperm maturation’, Gordon Research Conferences: Fertilization & Activation of Development. Program, Plymouth, UK (2007) [E3]

Baker Mark Andrew, Curry Benjamin John, Aitken Robert John, ’Inactivation of C-ABL Via PKA During Capacitation of Mouse Spermatozoa’, Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]

Baker Mark Andrew, Reeves Glenn E, Aitken Robert John, ’New Approaches Towards the Proteomic Analysis of the Human Spermatozoon’, Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]

Baker Mark Andrew, Reeves Gabi Monika, Aitken Robert John, ’New approaches towards the proteomic analysis of the human spermatozoon’, Book of Abstracts, Chicago, Illinois (2006) [E3]

Aitken Robert John, Baker Mark Andrew, Lee Yun Hwa, Lin Minjie, Nixon Brett, ’Proteomic Changes in Mouse Spermatozoa During Epididymal Transit’, Abstracts, Chatel-Guyon, Auvergne, France (2006) [E3]

Baker Mark Andrew, Hetherington Louise, Ecroyd Heath William, Roman Shaun Daryl, Aitken Robert John, ’Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation’, ComBio Combined Conference Abstracts, Melbourne (2003) [E3]

Aitken Robert John, Baker Mark Andrew, Krutskikh A, ’Oxidative stress and redox regulation in the epididymis’, Epididymis III. Third International Conference on the Epididymis., Charlottesville, Virginia, USA (2002) [E3]

Baker Mark Andrew, Krutskikh A, Aitken Robert John, ’Redox regulation of sperm function’, Proceedings of the Thirty-third annual Conference of the Society for Reproductive Biology, Adelaide, SA (2002) [E3]

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