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Dr Ian Grainge

Work Phone 4921 7238
Fax 4921 5472
Email
Office BG09, Biological Sciences

Publications

For items published while at an institution other that the University of Newcastle, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapters In A Book (4 outputs)

Chapter in A1 Book (B1) (4 outputs)

Year Citation Link
2007 GRAINGE I, SHERRATT D, 'Site specific recombination', Topics in Current Genetics: Molecular Genetics of Recombination, Springer, Berlin 1423-1433 (2007) [B1]
2005 GRAINGE I R, JAYARAM M, 'Introduction to site-specific recombination', The Dynamic Bacterial Genome, Cambridge University Press, Cambridge 33-82 (2005) [B1]
2005 VOZIYANOV Y, GRAINGE I R, JAYARAM M, 'Applications of fungal site-specific recombination as a tool in biotechnology and basic biology', Applied Mycology and Biotechnology, Elsevier, Amsterdam 189-210 (2005) [B1]
2002 JAYARAM M, GRAINGE I R, TRIBBLE G D, 'Site-specific DNA recombination mediated by the Flp protein of Saccharomyces cerevisiae', Mobile DNA II, ASM Press, Washington 192-218 (2002) [B1]
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Journal Articles (23 outputs)

Refereed Article in a Scholarly Journal (C1) (23 outputs)

Year Citation Link
2011 Grainge Ian Richard, Lesterlin Christian, Sherratt David J, 'Activation of XerCD-dif recombination by the FtsK DNA translocase', Nucleic Acids Research, 39 5140-5148 (2011) [C1]
2010 CROZAT E, MEGLIO A, ALLEMAND J, CHIVERS C E, HOWARTH M, VENIEN-BRYAN C, GRAINGE I R, SHERRATT D J, 'Separating speed and ability to displace roadblocks during DNA translocation by FtsK.', The EMBO Journal, 29 1423-1433 (2010) [C1]
2010 SHERRATT D J, ARCISZEWSKA L, CROZAT E, GRAHAM J, GRAINGE I R, 'The Escherichia coli DNA translocase FtsK.', Biochemical Society Transactions, 38 395-398 (2010) [C1]
2010 Crozat Estelle, Grainge Ian Richard, 'FtsK DNA translocase: The fast motor that knows where it's going', ChemBioChem, 11 2232-2243 (2010) [C1] Nova
2010 Grainge Ian Richard, 'FtsK - a bacterial cell division checkpoint?', Molecular Microbiology, 78 1055-1057 (2010) [C1] Nova
2008 ATANASSOVA N, GRAINGE I R, 'Biochemical Characterization of the Minichromosome Maintenance (MCM) Protein of the Crenarchaeote Aeropyrum pernix and Its Interactions with the Origin Recognition Complex (ORC) Proteins', Biochemistry, 47 1336-1337 (2008) [C1]
2008 GRAINGE I R, 'Sporulation: SpoIIIE is the key to cell differentiation', Current Biology, 18 871-872 (2008) [C1]
2008 LOWE J, ELLONEN A, ALLEN M D, ATKINSON C, SHERRATT D J, GRAINGE I R, 'Molecular mechanism of sequence-directed DNA loading and translocation by FtsK', Molecular Cell, 31 498-509 (2008) [C1]
2007 GRAINGE I R, BREGU M, VAZQUEZ M, SIVANATHAN V, IP S C, SHERRATT D J, 'Unlinking chromosome catenanes in vivo by site-specific recombination', The EMBO Journal, 26 4228-4238 (2007) [C1]
2006 GRAINGE I R, GAUDIER M, SCHUWIRTH B S, WESTCOTT S L, SANDALL J, ATANASSOVA N, WIGLEY D B, 'Biochemical analysis of a DNA replication origin in the archaeon Aeropyrum pernix', Journal of Molecular Biology, 363 355-369 (2006) [C1]
2006 POSSOZ C, FELIPE S, GRAINGE I R, SHERRATT D J, 'Tracking of controlled Escherichia coli replication fork stalling and restart at repressor-bound DNA in vivo', The EMBO Journal, 25 2596-2604 (2006) [C1]
2004 SINGLETON M R, MORALES R, GRAINGE I R, COOK N, ISUPOV M N, WIGLEY D B, 'Conformational changes induced by nucleotide binding in Cdc6/ORC from Aeropyrum pernix', Journal of Molecular Biology, 343 547-557 (2004) [C1]
2003 GRAINGE I R, SCAIFE S, WIGLEY D B, 'Biochemical analysis of components of the pre-replication complex of Archaeoglobus fulgidus', Nucleic Acids Research, 31 4888-4898 (2003) [C1]
2002 GRAINGE I R, PATHANIA S, VOLOGODSKII A, HARSHEY R, JAYARAM M, 'Symmetric DNA sites are functionally asymmetric within Flp and Cre site-specific DNA recombination synapses', Journal of Molecular Biology, 320 515-527 (2002) [C1]
2001 FROHLICH R F, HANSEN S G, LISBY M, GRAINGE I R, WESTERGAARD O, JAYARAM M, KNUDSEN B R, 'Inhibition of Flp recombinase by the topoisomerase I-targeting drugs, camptothecin and NSC-314622', Journal of Biological Chemistry, 276 6993-6997 (2001) [C1]
2001 GRAINGE I R, LEE J, XU C J, JAYARAM M, ' DNA recombination and RNA cleavage activities of the Flp protein: Roles of two histidine residues in the orientation and activation of the nucleophile for strand cleavage', Journal of Molecular Biology, 314 717-733 (2001) [C1]
2001 SAU A K, TRIBBLE G D, GRAINGE I R, FROHLICH R F, KNUDSEN B R, JAYARAM M, 'Biochemical and kinetic analysis of the RNase active sites of the integrase/tyrosine family site-specific recombinases', Journal of Biological Chemistry, 276 4661-4662 (2001) [C1]
2000 GRAINGE I R, BUCK D E, JAYARAM M, 'Geometry of site alignment during int family recombination: Antiparallel synapsis by the Flp recombinase', Journal of Molecular Biology, 298 749-764 (2000) [C1]
1999 GRAINGE I R, SHERRATT D J, 'Xer site-specific recombination - DNA strand rejoining by recombinase XerC', Journal of Biological Chemistry, 274 6763-6769 (1999) [C1]
1999 LEE J, JAYARAM M, GRAINGE I R, ' Wild-type Flp recombinase cleaves DNA in trans', The EMBO Journal, 18 784-791 (1999) [C1]
1998 XU C J, GRAINGE I R, LEE J, HARSHEY R, JAYARAM M, 'Unveiling two distinct ribonuclease activities and a topoisomerase activity in a site-specific DNA recombinase', Molecular Cell, 1 729-739 (1998) [C1]
1997 ARCISZEWSKA L, GRAINGE I R, SHERRATT D J, 'Action of site-specific recombinases XerC and XerD on tethered Holliday junctions', The EMBO Journal, 16 3731-3743 (1997) [C1]
1995 ARCISZEWSKA L, GRAINGE I R, SHERRATT D J, 'EFFECTS OF HOLLIDAY JUNCTION POSITION ON XER-MEDIATED RECOMBINATION IN-VITRO', The EMBO Journal, 14 2651-2660 (1995) [C1]
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Review (1 outputs)

A Substantial Review of an Entire Field of Study (D1) (1 outputs)

Year Citation Link
1999 GRAINGE I R, MAKKUNI J, 'The integrase family of recombinases: organization and function of the active site (1999) [D1]