Dr Rick Thorne

Work Phone	(02) 4921 7860
Fax	(02) 4921 7867
Email	Rick.Thorne@newcastle.edu.au
Office	LS3-33, Life Sciences

Highlighted Publications

Year	Citation	Link
2006	Tzircotis George, Thorne Rick Francis, Isacke Claire M, 'Directional sensing of a phorbol ester gradient requires CD44 and is regulated by CD44 phosphorylation', Oncogene, 25 7401-7410 (2006) [C1]
2005	Tzircotis George, Thorne Rick Francis, Isacke Clare M, 'Chemotaxis towards hyaluronan is dependent on CD44 expression and modulated by cell type variation in CD44-hyaluronan binding', Journal of Cell Science, 118 5119-5128 (2005) [C1]

Publications

For items published while at an institution other that the University of Newcastle, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Journal Articles (39 outputs)

Refereed Article in a Scholarly Journal (C1) (39 outputs)

Year	Citation	Link
2012	De Bock Charles Edo, Ardjmand Ghahestani Alireza, Molloy T J, Bone S M, Johnstone Daniel McKenzie, Campbell Daniel Marshall, Shipman Kristy Lea, Yeadon T M, Holst J, Spanevello M D, Nelmes G, Catchpoole D R, Lincz Lisa, Boyd A W, Burns Gordon Frood, Thorne Rick Francis, 'The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia', Leukemia, 26 918-926 (2012) [C1]
2012	Mhaidat Nizar M, Abdul-Razzak Kalid K, Alkofahi Ahmad S, Alsarhan Aseera M, Aldaher Ahmad N, Thorne Rick Francis, 'Altholactone induces apoptotic cell death in human colorectal cancer cells', Phytotherapy Research, 26 926-931 (2012) [C1]
2012	Tay Kwang Hong, Jin L, Tseng Hsin Yi, Jiang Chen Chen, Ye Yan, Thorne Rick Francis, Liu T, Guo S T, Verrills Nicole Margaret, Hersey P, Zhang Xu Dong, 'Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress', Cell Death and Disease, 3 e337 (2012) [C1]
2011	Alkhatatbeh Mohammad Jamil, Mhaidat N M, Enjeti A K, Lincz Lisa, Thorne Rick Francis, 'The putative diabetic plasma marker, soluble CD36, is non-cleaved, non-soluble and entirely associated with microparticles', Journal of Thrombosis and Haemostasis, 9 844-851 (2011) [C1]
2011	Dong L, Jiang Chen Chen, Thorne Rick Francis, Croft A, Yang F, Liu H, De Bock Charles Edo, Hersey Peter, Zhang Xu Dong, 'Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress', Oncogene, 30 3716-3726 (2011) [C1]
2011	Jiang Chen Chen, Lai Fritz, Thorne Rick Francis, Yang Fan, Liu Hao, Hersey Peter, Zhang Xu Dong, 'MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720', Clinical Cancer Research, 17 721-730 (2011) [C1]
2011	Jin Lei, Hu Wang Lai, Jiang Chen Chen, Wang Jia Xu, Han Chuan Chun, Chu Ping, Zhang Lin Jie, Thorne Rick Francis, Wilmott James, Scolyer Richard A, Hersey Peter, Zhang Xu Dong, Wu Mian, 'MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma', Proceedings of the National Academy of Sciences, 108 15840-15845 (2011) [C1]
2011	Sadeqzadeh Elham, De Bock Charles Edo, Zhang Xu Dong, Shipman Kristy Lea, Scott Naomi Marie, Song Chaojun, Yeadon Trina, Salum De Oliveira Camila, Jin Boquan, Hersey Peter, Boyd Andrew W, Burns Gordon Frood, Thorne Rick Francis, 'Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products', Journal of Biological Chemistry, 286 28181-28191 (2011) [C1]
2010	Jiang C C, Lai F, Tay K H, Croft A, Rizos H, Becker T M, Yang F, Liu H, Thorne Rick Francis, Hersey Peter, Zhang Xu Dong, 'Apoptosis of human melanoma cells induced by inhibition of B-RAF(V600E) involves preferential splicing of bim(S)', Cell Death & Disease, 1 e69 (2010) [C1]
2010	Mao Zhi Gang, Jiang Chen Chen, Thorne Rick Francis, Hersey Peter, Zhang Xu Dong, 'TRAIL-induced apoptosis of human melanoma cells involves activation of caspase-4', Apoptosis, 15 1211-1222 (2010) [C1]
2010	Thorne Rick Francis, Ralston Kylie Jane, De Bock Charles Edo, Mhaidat Nizar M, Zhang Xu Dong, Boyd Andrew W, Burns Gordon Frood, 'Palmitoylation of CD36/FAT regulates the rate of its post-transcriptional processing in the endoplasmic reticulum', Biochimica et Biophysica Acta - Molecular Cell Research, 1803 1298-1307 (2010) [C1]
2010	Tseng Hsin-Yi, Jiang Chen Chen, Croft Amanda, Croft Amanda, Thorne Rick Francis, Yang Fan, Liu Hao, Hersey Peter, Zhang Xu Dong, 'Contrasting effects of Nutlin-3 on TRAIL - and Docetaxel-induced Apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells', Molecular Cancer Therapeutics, 9 3363-3374 (2010) [C1]
2010	Yang F, Tay K H, Dong L, Thorne Rick Francis, Jiang C C, Yang E, Tseng H Y, Liu H, Christopherson R, Hersey Peter, Zhang Xu Dong, 'Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIPL from degradation by the E3 ligase itch in human melanoma cells', Cell Death and Differentiation, 17 1354-1367 (2010) [C1]
2010	Zhang Xinhai, Thorne Rick Francis, Wagner Thomas E, Wei Yanzhang, 'Regulatory T cells and cancer therapy: An old story with a new hope', Current Cancer Therapy Reviews, 6 34-40 (2010) [C1]
2009	Jiang Chen Chen, Yang Fan, Thorne Rick Francis, Zhu Bi Ke, Hersey Peter, Zhang Xu Dong, 'Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt', Neoplasia, 11 436-447 (2009) [C1]
2009	Mhaidat Nizar M, Alali Feras Q, Matalqah Sina M, Matalka Ismail I, Jaradat Saied A, Al-Sawalha Nour A, Thorne Rick Francis, 'Inhibition of MEK sensitizes paclitaxel-induced apoptosis of human colorectal cancer cells by downregulation of GRP78', Anti-Cancer Drugs, 20 601-606 (2009) [C1]
2009	Zhang Lin Jie, Chen Si, Wu Pin, Hu Chun Song, Thorne Rick Francis, Luo Chang Ming, Hersey Peter, Zhang Xu Dong, 'Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells', Cancer Letters, 274 40-46 (2009) [C1]
2008	Chen Li Hua, Jiang Chen Chen, Watts Ralph, Thorne Rick Francis, Kiejda Kelly Anne, Zhang Xu Dong, Hersey Peter, 'Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein', Cancer Research, 68 834-842 (2008) [C1]
2008	Jiang Chen Chen, Lucas Keryn, Kiejda Kelly Anne, Wade Margaret, Debock Charles E, Thorne Rick Francis, Allen John, Hersey Peter, Zhang Xu Dong, 'Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress', Cancer Research, 68 6708-6717 (2008) [C1]
2008	Mhaidat Nizar M, Thorne Rick Francis, De Bock Charles Edo, Zhang Xu Dong, Hersey Peter, 'Melanoma cell sensitivity to docetaxal-induced apoptosis is determined by class III beta-tubulin levels', FEBS Letters, 582 267-272 (2008) [C1]
2008	Mhaidat Nizar M, Thorne Rick Francis, Zhang Xu Dong, Hersey Peter, 'Involvement of endoplasmic reticulum stress in Docetaxel-induced JNK-dependent apoptosis of human melanoma', Apoptosis, 13 1505-1512 (2008) [C1]
2008	Zhang Lin Jie, Hao Yuan Zhang, Hu Chun Song, Ye Yan, Xie Qi Peng, Thorne Rick Francis, Hersey Peter, Zhang Xu Dong, 'Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells', Anti-Cancer Drugs, 19 159-166 (2008) [C1]
2007	Chen Li Hua, Jiang Chen Chen, Kiejda Kelly Anne, Wang Yu Fang, Thorne Rick Francis, Zhang Xu Dong, Hersey Peter, 'Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response', Carcinogenesis, 28 2328-2336 (2007) [C1]
2007	Jiang Chen Chen, Li H C, Gillespie S, Kiejda Kelly Anne, Mhaidat N, Yu F W, Thorne Rick Francis, Zhang Xu Dong, Hersey Peter, 'Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response', Cancer Research, 67 5880-5888 (2007) [C1]
2007	Mhaidat N M, Thorne Rick Francis, Zhang Xu Dong, Hersey Peter, 'Regulation of docetaxel-induced apoptosis of human melanoma cells by different isoforms of protein kinase C', Molecular Cancer Research, 5 1073-1081 (2007) [C1]
2007	Thorne Rick Francis, Mhaidat Nizar, Ralston Kylie Jane, Burns Gordon Frood, 'CD36 is a receptor for oxidized high density lipoprotein: Implications for the development of atherosclerosis', FEBS Letters, 581 1227-1232 (2007) [C1]
2007	Thorne Rick Francis, Mhaidat Nizar, Ralston Kylie Jane, Burns Gordon Frood, 'Shed gangliosides provide detergent-independent evidence for type-3 glycosynapses', Biochemical and Biophysical Research Communications, 356 306-311 (2007) [C1]
2006	Thorne Rick Francis, Law Estelle, Elith Craig A, Ralston Kylie Jane, Bates Richard Craig, Burns Gordon Frood, 'The association between CD36 and Lyn protein tyrosine kinase is mediated by lipid', Biochemical and Biophysical Research Communications, 351 51-56 (2006) [C1]
2006	Thorne Rick Francis, Zhang X H, Song C J, Jin B Q, Burns Gordon Frood, 'Novel immunoblotting monoclonal antibodies against human and rat CD36/fat used to identify an isoform of CD36 in rat muscle', DNA and Cell Biology, 25 302-311 (2006) [C1]
2006	Tzircotis George, Thorne Rick Francis, Isacke Claire M, 'Directional sensing of a phorbol ester gradient requires CD44 and is regulated by CD44 phosphorylation', Oncogene, 25 7401-7410 (2006) [C1]
2005	Tzircotis George, Thorne Rick Francis, Isacke Clare M, 'Chemotaxis towards hyaluronan is dependent on CD44 expression and modulated by cell type variation in CD44-hyaluronan binding', Journal of Cell Science, 118 5119-5128 (2005) [C1]
2004	THORNE R F, Legg J W, Isacke C M, 'The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events.', Journal of Cell Science, 117 373-380 (2004) [C1]
2004	Ralston Kylie Jane, Hird Sl, Zhang Xinhai, Scott Judith Louise, Jin B, Thorne Rick Francis, Berndt Mc, Boyd Aw, Burns Gordon Frood, 'The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large', Journal of Biological Chemistry, 279 33816-33828 (2004) [C1]
2003	Sullivan A, Uff C R, Isacke C M, THORNE R F, 'PACE-1, a novel protein that interacts with the C-terminal domain of ezrin', Experimental Cell Research, 284 224-238 (2003) [C1]
2000	Shafren D R, Dorahy D J, THORNE R F, Barry R D, 'Cytoplasmic interactions between decay-accelerating factor and intercellular adhesion molecule-1 are not required for coxsackievirus A21 cell infection', Journal of General Virology, 81 889-894 (2000) [C1]
2000	Gruarin P, Ulliers D, Thorne Rick Francis, Alessio M, 'Methionine 156 in the immunodominant domain on CD36 contributes to define the epitope recognized by the NL07 MoAb', Molecular and Cellular Biochemistry, 214 89-95 (2000) [C1]
2000	Thorne Rick Francis, Marshall Jf, Shafren Dr, Gibson Pg, Hart Ir, Burns Gordon Frood, 'The Integrins (alpha)3(beta)1 Physically and functionally Associate with CD36 in Human Melanoma Cells', The Journal of Biological Chemistry, 275 No. 45 35264-35275 (2000) [C1]
1998	Bates Richard Craig, Elith C A, Thorne Rick Francis, Burns Gordon Frood, 'Engagement of Variant CD44 confers resistance to anti-integrin antibody-mediated apoptosis in a colon carcinoma cell line', Cell Adhesion and Communication, 6 (1) 21-38 (1998) [C1]
1998	Shafren D R, Dorahy Douglas John, Thorne Rick Francis, Kinoshita T, Barry R D, Burns Gordon Frood, 'Antibody binding to individual short consensus repeats of decay-accelerating factor enhances enterovirus cell attachment and infectivity', The Journal of Immunology, 160 2318-2323 (1998) [C1]
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Conference Publication (12 outputs)

Extract of Paper (E3) (12 outputs)

Year	Citation	Link
2012	Li Jingjing, Imtiaz Mohammad Sahariq, Beard N A, Dulhunty A F, Thorne Rick Francis, Van Helden Dirk Ferdinand, Laver Derek Rowland, 'Adrenergic stimulation alters RyR2 regulation by Ca2+ and Mg2+', Heart, Lung and Circulation: Abstracts of ISHR Auckland Workshop, Auckland, NZ (2012) [E3]
2011	Alkhatatbeh Mohammad Jamil, Mhaidat N M, Enjeti A K, Lincz L F, Thorne Rick Francis, 'Circulating plasma CD36+microparticles as a marker of type 2 diabetes and its complications', Clinical Biochemistry, Mashhad, Iran (2011) [E3]
2011	Ardjmand Ghahestani Alireza, De Bock Charles Edo, Molloy Timothy J, Bone Simon M, Johnstone Daniel McKenzie, Campbell Daniel Marshall, Shipman Kristy Lea, Yeadon Trina M, Hoist Jeff, Spanevello Mark D, Catchpoole D R, Lincz Lisa, Boyd Andrew W, Burns Gordon Frood, Thorne Rick Francis, 'Altered expression of Fat1 cadherin, a novel tumor marker for acute lymphoblastic leukemia', Clinical Biochemistry, Mashhad, Iran (2011) [E3]
2011	Sadeqzadeh Elham, Hersey Peter, Zhang Xu Dong, Debock Charles, Boyd Andrew, Burns Gordon Frood, Thorne Rick Francis, 'Aberrant processing of Fat1 Cadherin in human cancer', Clinical Biochemistry, Mashhad, Iran (2011) [E3]
2011	Ye Y, Jin L, Wilmott J, Hu W L, Thorne Rick Francis, Dong Li, De Bock Charles Edo, Jiang Chen Chen, Rizos H, Wu M, Zhang L J, Scolyer R, Hersey Peter, Zhang Xu Dong, 'Phosphatidylinositol 4,5-Bisphosphate 5-Phosphatase A regulates PI3K/Akt signaling in human melanoma cells', Pigment Cell & Melanoma Research, Tampa, FL (2011) [E3]
2010	Chen Li H, Yang Fan, Tay Kwang Hong, Dong Li, Thorne Rick Francis, Jiang Chen Chen, Yang Eva, Tseng Hsin Yi, Liu Hao, Christopherson Richard, Hersey Peter, Zhang Xu Dong, 'Cystatin B inhibition of TRAIL-induced apoptosis is associated with protection of FLIP_Lfrom degradation by the E3 ligase itch human melanoma cells', Pigment Cell & Melanoma Research, Sydney, Australia (2010) [E3]
2010	Dong Li, Jiang Chen Chen, Thorne Rick Francis, Yang Fan, Liu Hao, De Bock Charles Edo, Hersey Peter, Zhang Xu Dong, 'Transcriptional up-regulation of Mcl-1 by ETS1 down-stream of XBP-1 in melanoma cells upon ER stress', Pigment Cell & Melanoma Research, Sydney, Australia (2010) [E3]
2010	Jiang Chen Chen, Zhuang Li Qing, Dong Li, Thorne Rick Francis, Lavis Christopher James, Hersey Peter, Zhang Xu Dong, 'Adaptation to ER stress as a driver of increased expression of Mcl-1 with melanoma progression', AACR 101st Annual Meeting 2010. Abstracts, Washington, DC (2010) [E3]
2010	Salum De Oliveira Camila, Yan Xu Guang, Hersey Peter, Zhang Xu Dong, Thorne Rick Francis, 'The role of MIF signaling in melanoma progression', AACR 101st Annual Meeting 2010. Abstracts, Washington, DC (2010) [E3]
2010	Yang Xiang Min, Chen Li Hua, Jiang Chen Chen, De Bock Charles Edo, Thorne Rick Francis, Hersey Peter, Zhang Xu Dong, '40p53 is up-regulated and plays a role in antagonizing p53-mediated apoptosis in human melanoma', Pigment Cell & Melanoma Research, Sydney, Australia (2010) [E3]
2010	Zhang Xu Dong, Jiang Chen Chen, Lai Fritz, Croft Amanda, Tay Kwang Hong, Thorne Rick Francis, Becker Therese, Rizos Helen, Hersey Peter, 'Apoptotic response of mutant B-RAF human melanoma cells to a B-RAF inhibitor involves increased splicing production of BimS', AACR 101st Annual Meeting 2010. Abstracts, Washington, DC (2010) [E3]
2001	Law Estelle, Thorne Rick Francis, Zhang Xi Yi, Burns Gordon Frood, Boyd Aw, 'Fat Protocadherin as a Mechanical Regulator of Melanoma Cell Migration', Melanoma Research, Venice - 28 February to 3 March 2001 (2001) [E3]
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