Dr Steven Maltby

Biography

I completed my PhD studies with Dr Kelly McNagny at The Biomedical Research Centre, University of British Columbia in Vancouver, BC, Canada. My research focused on the role of CD34 (and the related molecule podocalyxin) in immune responses, using mouse models of disease. Those studies identified the importance of CD34 for efficient eosinophil and mast cell migration to sites of inflammation during disease. Further, I demonstrated that loss of CD34 expression (using transgenic Cd34-/- animals) resulted in reduced disease severity in mouse models of asthma and ulcerative colitis.

My current research focus is aimed at characterizing changes in the bone marrow during disease and infection. The aim of these studies is to identify key molecules involved in feedback from sites of infection/inflammation to the bone marrow and alterations to hematopoietic stem and progenitor cells.

Qualifications

• PhD, University of British Columbia - Canada, 2010
• Bachelor of Science, University of British Columbia - Canada, 2004

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Research

Research keywords

• Asthma
• Disease Models
• Eosinophils
• Hematopoiesis
• Immunology

Research expertise

Main Research Focus Areas:

Bone Marrow Responses to Infection and Disease

MicroRNA

Immune Cell Activation and Migration

Eosinophil Regulation

Languages

• English

Fields of Research

Code	Description	Percentage
110700	Immunology	50
110309	Infectious Diseases	30
110316	Pathology	20

Centres and Groups

Centre

• Hunter Medical Research Institute
• PRC - Priority Research Centre for Asthma & Respiratory Diseases

Group

• Hunter Medical Research Institute - VIVA

Awards

Research Award.

2012	Postdoctoral Research Fellowship Canadian Institute of Health Research (CIHR) (Canada) Canadian national research fellowship
2012	Postdoctoral Research Fellowship University of Newcastle (Australia) University of Newcastle research fellowship

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Teaching

Teaching keywords

• Immunology

Teaching expertise

Immunology