Prof. Xu Zhang

Work Phone	(02) 4921 8906
Fax	(02) 4921 7311
Email	Xu.Zhang@newcastle.edu.au
Office	LS3-49, Life Sciences Building

Funding

Summary

Number of grants	34
Total funding	$5,137,426

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (4 grants)

Functional consequences of epigenetic repression of PIB5PA in melanoma$359,250
Funding Body: Cancer Council NSW

Project Team
Professor Xu Zhang, Dr Helen Rizos, Doctor Rick Thorne, Doctor Chen Chen Jiang
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$359,250	2013	2015
GNo:G1200386

Targeting PP2A to improve the therapeutic efficacy of mutant BRAF inhibitors in melanoma$359,250
Funding Body: Cancer Council NSW

Project Team
Professor Xu Zhang, Doctor Nikki Verrills, Doctor Chen Chen Jiang
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$359,250	2013	2015
GNo:G1200388

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Pradeep Tanwar, Professor Eileen McLaughlin, Professor Xu Zhang, Professor Robert Callister, Associate Professor Phillip Dickson, Professor Hubert Hondermarck, Doctor Jean-Marie Sontag, Associate Professor Dirk Van Helden, Doctor Doug Smith, Doctor Phil Jobling, Associate Professor Estelle Sontag, Associate Professor Paul Tooney, Doctor Susan Hua, Doctor Janet Holt, Doctor Jay Horvat, Doctor Liz Milward, Professor Adam McCluskey, Associate Professor Brett Nixon, Doctor Rebecca Lim, Associate Professor Alan Brichta
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$35,000	2013	2013
GNo:G1201185

Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Jude Weidenhofer, Doctor Rick Thorne, Doctor Kathryn Skelding, Doctor Nikki Verrills, Doctor Pradeep Tanwar, Associate Professor Phillip Dickson, Doctor Murray Cairns, Professor Hubert Hondermarck, Professor Xu Zhang, Associate Professor Estelle Sontag, Doctor Chen Chen Jiang, Doctor Liz Milward, Doctor Jean-Marie Sontag, Associate Professor Paul Tooney, Doctor Severine Roselli, Doctor Matt Dun, Doctor Chris Dayas, Doctor Lin Kooi Ong, Associate Professor Dirk Van Helden, Mr Ben Copeland, Ms Gabrielle Briggs, Conjoint Professor Leonie Ashman, Professor John Rostas
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$24,596	2013	2013
GNo:G1201189

2012 (5 grants)

Targeting Histone Deacetylases to Overcome Resistance of BRAFV600E Melanoma Cells to Apoptosis$346,974
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Xu Zhang, Conjoint Professor Peter Hersey, Dr Tao Liu, Doctor Chen Chen Jiang, Doctor Rick Thorne
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$346,974	2012	2014
GNo:G1100133

The Hunter Cancer Biobank (HCB): Maximising community value through validation, annotation and distribution throughout NSW$294,301
Funding Body: Cancer Institute NSW

Project Team
Professor John Forbes, Conjoint Professor Stephen Ackland, Professor Rodney Scott, Conjoint Associate Professor Barbara Young, Professor Hubert Hondermarck, Conjoint Professor Leonie Ashman, Professor Xu Zhang, Doctor Kelly Kiejda, Doctor Nikki Verrills, Doctor Jennette Sakoff, Ms Janine Lombard, Doctor Jude Weidenhofer, Doctor Pradeep Tanwar
Scheme		Role
Infrastructure Grants		Investigator
Total Amount	Funding Start	Funding Finish
$294,301	2012	2014
GNo:G1200798

High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Rick Thorne, Professor Xu Zhang, Professor Hubert Hondermarck, Conjoint Professor Stephen Ackland, Doctor Lisa Lincz, Doctor Jennette Sakoff, Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$143,394	2012	2012
GNo:G1200555

Microscopic illumination system for advanced fluorescent protein technology$34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Rick Thorne, Professor Xu Zhang, Doctor Murray Cairns, Doctor Nikki Verrills, Doctor Charles De Bock, Doctor Jude Weidenhofer, Doctor Severine Roselli, Doctor Kathryn Skelding, Conjoint Professor Leonie Ashman, Professor Hubert Hondermarck
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$34,000	2012	2012
GNo:G1100983

A p53-Mediated Pro-Survival Signaling Pathway in Human Melanoma Progression and Resistance to Treatment$20,000
Funding Body: University of Newcastle

Project Team
Professor Xu Zhang, Doctor Rick Thorne, Doctor Chen Chen Jiang
Scheme		Role
Near Miss Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2012	2012
GNo:G1200672

2011 (6 grants)

Overcoming resistance of human metastatic melanoma to treatment$570,640
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Xu Zhang
Scheme	Role
Research Fellowships	Chief Investigator
Total Amount	Funding Start	Funding Finish
$570,640	2011	2015
GNo:G1000048

Targeting pro-survival mechanisms to sensitize human melanoma to immunotherapy$359,250
Funding Body: Cancer Council NSW

Project Team
Professor Xu Zhang, Doctor Ming Yang
Scheme	Role
Research Program	Chief Investigator
Total Amount	Funding Start	Funding Finish
$359,250	2011	2013
GNo:G1000379

Overcoming Resistance of Metastatic Melanoma to Treatment: 53 regulation of Mcl-1 via a microRNA-Mediated Pathway in Melanoma progression and Resistance to Chemotherapy$123,498
Funding Body: Cancer Institute NSW

Project Team
Professor Xu Zhang
Scheme	Role
Career Development Fellowship	Chief Investigator
Total Amount	Funding Start	Funding Finish
$123,498	2011	2014
GNo:G1000815

Regulation of BimS splicing in response of human melanoma cells to inhibition of BRAFVV600E$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Chen Chen Jiang, Professor Xu Zhang
Scheme	Role
Project Grant	Investigator
Total Amount	Funding Start	Funding Finish
$25,000	2011	2011
GNo:G1000988

Targeting Pro-Survival Mechanisms to Sensitize Human Melanoma to Immunotherapy$25,000
Funding Body: University of Newcastle

Project Team
Professor Xu Zhang, Doctor Ming Yang
Scheme	Role
Near Miss Grant	Chief Investigator
Total Amount	Funding Start	Funding Finish
$25,000	2011	2011
GNo:G1001046

The Role of Phosphatidylinositol 4, 5-Bisphosphate 5-Phosphatase A (PIB5PA) in Regulation of PI3K/Akt Signalling in Melanoma$24,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Xu Zhang, Doctor Chen Chen Jiang
Scheme	Role
Project Grant	Chief Investigator
Total Amount	Funding Start	Funding Finish
$24,000	2011	2013
GNo:G1101121

2010 (4 grants)

Transcriptional regulation of the expression of Mcl-1 in melanoma cell under ER stress$144,300
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Hersey, Professor Xu Zhang, Doctor Li Dong
Scheme		Role
Training (Postdoctoral) Fellowships - Australia-China Exchange Fellowships		Investigator
Total Amount	Funding Start	Funding Finish
$144,300	2010	2013
GNo:G0190308

Melanoma Institute Australia Translational Research Program$58,405
Funding Body: Cancer Institute NSW

Project Team
Professor Graham Mann, Professor John Thompson, Professor R Kefford, Clinical Professor Richard Scolyer, Professor Scott Menzies, Associate Professor Andrew Spillane, Conjoint Professor Peter Hersey, Dr Helen Rizos, Professor Xu Zhang, Professor Richard Christopherson
Scheme		Role
Translational Program Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$58,405	2010	2015
GNo:G1200975

Targeting Pro-Survival Mechanisms to Sensitize Human Melanoma to Immunotherapy$48,200
Funding Body: Cancer Institute NSW

Project Team
Professor Xu Zhang
Scheme	Role
Research Innovation Grants	Chief Investigator
Total Amount	Funding Start	Funding Finish
$48,200	2010	2010
GNo:G0190555

The role of micro-RNA-149 in Regulation of Mcl-1 in Human Melanoma under stress$20,000
Funding Body: Hunter Children`s Research Foundation

Project Team
Doctor Chen Chen Jiang, Professor Xu Zhang
Scheme	Role
Research Grant	Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2010	2010
GNo:G0900189

2009 (4 grants)

Targeting adaptive mechanisms to endoplasmic reticulum stress in melanoma$491,250
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Xu Zhang, Conjoint Professor Peter Hersey, Doctor Rick Thorne
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$491,250	2009	2011
GNo:G0188902

Targeting p53 isoforms, delta-40p53 and p53-beta, to promote chemo-sensitivity in human melanoma$272,000
Funding Body: Cancer Council NSW

Project Team
Professor Xu Zhang, Conjoint Professor Peter Hersey, Doctor Kelly Kiejda
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$272,000	2009	2011
GNo:G0188913

Targeting p53 isoforms, delta-40p53 and p53-beta, to promote chemo-sensitivity in human melanoma$75,000
Funding Body: Cancer Australia

Project Team
Doctor Kelly Kiejda, Professor Xu Zhang, Conjoint Professor Peter Hersey
Scheme		Role
Priority-driven Collaborative Cancer Research		Investigator
Total Amount	Funding Start	Funding Finish
$75,000	2009	2010
GNo:G0188914

FACSAria$30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Rick Thorne, Doctor Severine Roselli, Professor Xu Zhang, Dr Charles De Bock, Conjoint Professor Peter Hersey, Professor Gordon Burns
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$30,000	2009	2009
GNo:G0189846

2008 (1 grants)

Colibri high-performance LED illumination system for fluorescence live cell microscopy$23,225
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Rick Thorne, Dr Charles De Bock, Professor Xu Zhang, Doctor Lisa Lincz, Professor Gordon Burns, Conjoint Professor Peter Hersey, Associate Professor Dirk Van Helden, Conjoint Professor Keith Jones, Professor Roger Smith
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$23,225	2008	2008
GNo:G0188545

2007 (4 grants)

Characterization of p53 isoforms in human melanoma: do they play a role in chemoresistance?$75,000
Funding Body: Cure Cancer Australia Foundation

Scheme	Role
Project Grant	Chief Investigator
Total Amount	Funding Start	Funding Finish
$75,000	2007	2007
GNo:18105190

The role of p53 Isoforms in chemoresistances of human melanoma$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Xu Zhang, Doctor Kelly Kiejda
Scheme	Role
Project Grant	Chief Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2007	2007
GNo:G0187239

The role of p53 isoforms in chemoresistance of human melanoma. $0
Funding Body: Newcastle Mater Misericordiae Hospital

Scheme	Role
Small Grant	Chief Investigator
Total Amount	Funding Start	Funding Finish
$0	2007	2007
GNo:18105231

molecular predictors of risk, progression and treatment response in melanoma$0
Funding Body: National Health & Medical Research Council

Scheme	Role
Program Grant	Investigator
Total Amount	Funding Start	Funding Finish
$0	2007	2007
GNo:18105827

2006 (1 grants)

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle

Project Team
Professor Pablo Moscato, Professor Rodney Scott, Professor John Rostas, Professor John Forbes, Conjoint Professor Peter Hersey, Conjoint Professor Stephen Ackland, Conjoint Professor Wayne Smith, Emeritus Professor Peter Dunkley, Conjoint Professor Leonie Ashman, Professor John Attia, Associate Professor Phillip Dickson, Doctor Liz Milward, Professor Alistair Sim, Associate Professor Paul Tooney, Doctor Regina Berretta, Associate Professor David Sibbritt, Conjoint Professor Chris Levi, Professor Xu Zhang, Conjoint Associate Professor Patricia Crock, Conjoint Associate Professor Jeannette Lechner-Scott
Scheme		Role
Priority Research Centre		Investigator
Total Amount	Funding Start	Funding Finish
$621,143	2006	2013
GNo:G0186919

2005 (4 grants)

Overcoming resistance of human melanoma to chemotherapy$492,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Hersey, Professor Xu Zhang, Dr John Allen
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$492,750	2005	2007
GNo:G0183933

PULSE Young Medical Researcher of the Year Award$5,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Xu Zhang
Scheme	Role
Young Medical Researcher of the Year Award	Chief Investigator
Total Amount	Funding Start	Funding Finish
$5,000	2005	2005
GNo:G0184902

Overcoming Resistance of Melanoma to Chemotherapy$0
Funding Body: National Health & Medical Research Council

Scheme	Role
Project	Chief Investigator
Total Amount	Funding Start	Funding Finish
$0	2005	2007
GNo:18105841

Overcoming Resistance of Melanoma to Chemotherapy: Are Melanoma Stem Cells Key Targets? $0
Funding Body: Cancer Institute NSW

Scheme	Role
Career Development and Support Fellowship	Chief Investigator
Total Amount	Funding Start	Funding Finish
$0	2005	2007
GNo:18105807

2003 (1 grants)

Regulation of TNF Apoptosis Inducing Ligand (TRAIL) Receptor Expression in Human Melanoma Cells.$17,000
Funding Body: Hunter Medical Research Institute

The University of Newcastle, Australia

Prof. Xu Zhang

Funding

Summary

2013 (4 grants)

Functional consequences of epigenetic repression of PIB5PA in melanoma$359,250 Funding Body: Cancer Council NSW

Targeting PP2A to improve the therapeutic efficacy of mutant BRAF inhibitors in melanoma$359,250 Funding Body: Cancer Council NSW

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000 Funding Body: NHMRC (National Health & Medical Research Council)

Ultra-Low Temperature Cryogenic Freezer$24,596 Funding Body: NHMRC (National Health & Medical Research Council)

2012 (5 grants)

Targeting Histone Deacetylases to Overcome Resistance of BRAFV600E Melanoma Cells to Apoptosis$346,974 Funding Body: NHMRC (National Health & Medical Research Council)

The Hunter Cancer Biobank (HCB): Maximising community value through validation, annotation and distribution throughout NSW$294,301 Funding Body: Cancer Institute NSW

High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394 Funding Body: Hunter Medical Research Institute

Microscopic illumination system for advanced fluorescent protein technology$34,000 Funding Body: NHMRC (National Health & Medical Research Council)

A p53-Mediated Pro-Survival Signaling Pathway in Human Melanoma Progression and Resistance to Treatment$20,000 Funding Body: University of Newcastle

2011 (6 grants)

Overcoming resistance of human metastatic melanoma to treatment$570,640 Funding Body: NHMRC (National Health & Medical Research Council)

Targeting pro-survival mechanisms to sensitize human melanoma to immunotherapy$359,250 Funding Body: Cancer Council NSW

Overcoming Resistance of Metastatic Melanoma to Treatment: 53 regulation of Mcl-1 via a microRNA-Mediated Pathway in Melanoma progression and Resistance to Chemotherapy$123,498 Funding Body: Cancer Institute NSW

Regulation of BimS splicing in response of human melanoma cells to inhibition of BRAFVV600E$25,000 Funding Body: Hunter Medical Research Institute

Targeting Pro-Survival Mechanisms to Sensitize Human Melanoma to Immunotherapy$25,000 Funding Body: University of Newcastle

The Role of Phosphatidylinositol 4, 5-Bisphosphate 5-Phosphatase A (PIB5PA) in Regulation of PI3K/Akt Signalling in Melanoma$24,000 Funding Body: Hunter Medical Research Institute

2010 (4 grants)

Transcriptional regulation of the expression of Mcl-1 in melanoma cell under ER stress$144,300 Funding Body: NHMRC (National Health & Medical Research Council)

Melanoma Institute Australia Translational Research Program$58,405 Funding Body: Cancer Institute NSW

Targeting Pro-Survival Mechanisms to Sensitize Human Melanoma to Immunotherapy$48,200 Funding Body: Cancer Institute NSW

The role of micro-RNA-149 in Regulation of Mcl-1 in Human Melanoma under stress$20,000 Funding Body: Hunter Children`s Research Foundation